Summer Scholars in Genome Sciences & Medicine

摘要 对从事基因组科学和医学研究感兴趣的学生需要有很强的 核心基因组科学技术、分析技能和跨学科培训的基础。这个 此次续签申请的首要目标是继续提供高质量的指导性研究 在快速发展的基因组科学和精确医学领域，为有前途的学生提供经验。这个 为期10周的暑期计划围绕着基因组科学和医学方面的指导研究项目展开， 辅以授课和互动培训、研究研讨会和职业发展技能培养。 该计划向所有科学、技术、工程和数学专业的代表人数不足的学生开放。 他们是正在崛起的大二和大三学生。在这次续签中，我们正在扩大我们目前与North的合作伙伴关系 卡罗莱纳中央大学(NCCU)，一所历史上的黑人学院和大学(HBCU)，包括三个 在北卡罗来纳州增加HBCU，为暑期项目创建核心学生网络。教员 该项目的导师涵盖基础和应用基因组科学、数据 科学、转化基因组医学、生物信息学和计算生物学、工程学和 统计数据。杜克大学教职员工将举办一系列研究研讨会来补充这一研究经验。 和HBCU合作伙伴，并参观使用基因组科学技术或 他们在附近的研究三角公园的研究数据，以及其他与科学相关的社区服务 活动。鉴于人们越来越认识到数据科学的重要性，我们提议将 更多关于数据科学的学习机会，特别是向学生介绍其中一些工具和工作 使用开放访问数据集。此外，学生将有机会考虑受影响的更广泛的问题 通过每周一次的关于伦理、法律、社会和政策问题的讨论进行研究，并获得重要的 技能，如批判性阅读科学论文，领导讨论小组，进行文献评论，以及 做正式的陈述。所有学生将被要求在课程结束时提交他们的研究报告 程序。我们将对暑期学者进行年度调查，以收集他们所受教育的信息 以及STEM的职业道路，以衡量培训计划的影响。到目前为止，这个R25计划已经 在四个暑假期间支持了24名学生(2020年暑假没有学生因Covid而被录取 大多数学生是女性和非裔美国人。有几个学生已经成功地 在整个本科生涯中继续从事研究，并被顶尖毕业生录取 全国各地的项目和医学院。在此续期申请中建议的更改，以及 我们扩大了与该地区其他HBCU的伙伴关系，我们希望能对迅速变化的 科学和所需技能，并提高对该计划的认识和招募。总而言之，我们 旨在继续为代表不足的学生提供丰富的、高度跨学科的研究经验 基因组科学和医学。

SUMMARY Students interested in pursuing a career in genome sciences and medicine research will require a strong foundation of core genome sciences technology, analytical skills, and inter-disciplinary training. The overarching goal of this renewal application is to continue to provide a high-quality mentored research experience for promising students in the rapidly growing area of genome sciences and precision medicine. The 10-week summer program centers around a mentored research project in genome sciences and medicine, supplemented with didactic and interactive training, research seminars and career development skills-building. The program is open to all under-represented students in science, technology, engineering and mathematics who are rising sophomores and juniors. In this renewal, we are expanding our current partnership with North Carolina Central University (NCCU), an historically black college and university (HBCU), to include three additional HBCUs in North Carolina to create a core network of students for the summer program. Faculty mentors for this program span a wide range of disciplines in basic and applied genome sciences, data sciences, translational genomic medicine, bioinformatics and computational biology, engineering, and statistics. The research experience will be complemented by a series of research seminars by faculty at Duke and HBCU partners, and visits to sequencing facilities and companies using genome sciences technologies or data in their research in nearby Research Triangle Park, and other science-related community service activities. Given the increased recognition of the importance of data sciences, we are proposing to incorporate more learning opportunities on data sciences specifically to introduce students to some of these tools and work with open access datasets. In addition, students will have the opportunity to consider broader issues impacted by their research through a weekly discussion on the ethical, legal, social, and policy issues and gain important skills such as critical reading of scientific papers, leading a discussion group, conducting literature reviews, and making formal presentations. All students will be required to present their research at the conclusion of the program. We will administer annual surveys to summer scholars to gather information about their educational and career paths in STEM as a measure of the training program's impact. To date, this R25 program has supported 24 students over four summers (no students were accepted in summer 2020 due to Covid restrictions); a majority of students were female and African-American. Several students have successfully continued on in research throughout their undergraduate career and been accepted into leading graduate programs and medical schools around the country. With the proposed changes in this renewal application and our expanded partnerships with other HBCUs in the region, we hope to be responsive to the rapidly changing science and required skillsets and to increase awareness and recruitment for the program. In summary, we aim to continue to offer under-represented students a rich and highly interdisciplinary research experience in genome sciences and medicine.