Implementation Science and Equity: Pragmatic Implementation Science Methods (PrISM) Core

项目总结/摘要：实用实施科学方法（PrISM）核心 无论他们的研究训练或固有的人才，学习曲线的新研究人员在 实施科学可能是陡峭的。PrISM核心将为COBRE和其他KUMC调查人员提供 协调一致的跨学科支持对于在这一复杂领域取得成功至关重要。Prism的“团队科学” 这种方法将增加成功执行研究项目的可能性，并更好地准备项目 领导在合作研究环境中工作，这对实施科学至关重要。 目标1.建立一个执行科学方法核心，汇集执行方面的专门知识 科学理论和方法，并利用团队科学的原则，无缝集成专业知识， 生物统计学、医学信息学、混合方法研究和健康公平研究。Prism核心将 与首席执行官核心密切合作，为研究人员提供所需的研究地点和临床数据 支持推进卫生公平的务实实施研究。 目标2.在项目概念化、设计、执行和分析方面为COBRE项目负责人提供支持， 以及未来研究的计划。我们将使用普罗克特的经典实现模型的改编 研究创建一个框架，通过以公平为中心的每一步来支持项目领导 执行情况研究，包括：描述治疗方面的现有差距，制定执行方案， 战略，分析结果，报告结果，并设计新的，创新的研究建议，以扩大 或传播COBRE-supported工作的发现。 目标3。促进新的应用和实施科学方法，以解决卫生公平问题。棱镜 将与行政核心合作，确定和支持新的调查人员，并推进实施 科学方法，包括解决农村、少数民族和其他服务不足地区独特问题的方法 社区. PrISM还将不断扫描该领域，以确定以股权为重点的关键差距， 实施研究，以帮助确定COBRE工作的优先次序。 目标4。与行政核心合作，评估PrISM绩效。Prism核心 解决了堪萨斯大学医学中心以前未满足的需求，即建立一个专注于 实施科学。PrISM核心将提高机构和区域能力， 高质量的实施研究，将使研究项目更加务实，从而增加 COBRE对该领域产生持续和广泛影响的潜力。

PROJECT SUMMARY/ABSTRACT: PRAGMATIC IMPLEMENTATION SCIENCE METHODS (PrISM) CORE Regardless of their research training or inherent talent, the learning curve for new investigators in implementation science can be steep. The PrISM Core will provide COBRE and other KUMC investigators the coordinated, interdisciplinary support that is critical to success in this complex field. PrISM’s ‘team science’ approach will increase the likelihood of successful execution of research projects and better prepare Project Leads for working in the collaborative research environment that is critical to implementation science. Aim 1. Establish an Implementation Science methods Core bringing together expertise in implementation science theory and methods and leveraging the principles of team science to seamlessly integrate expertise in biostatistics, medical informatics, mixed methods research, and health equity research. The PrISM Core will work closely with the CEO core to provide researchers with access to research sites and clinical data needed to support pragmatic implementation research that advances health equity. Aim 2. Support COBRE Project Leads in project conceptualization, design, execution, and analysis, and plans for future research. We will use an adaptation of Proctor’s classic model of implementation research to create a framework for supporting Project Leads through each step of equity-focused implementation research, including: describing existing disparities in treatment, developing implementation strategies, analyzing outcomes, reporting results, and designing new, innovative research proposals to extend or disseminate findings from COBRE-supported work. Aim 3. Foster new applications and implementation science methods to address health equity. PrISM will work with the Administrative Core to identify and support new investigators and advance implementation science methods, including methods that address unique issues in rural, minority and other underserved communities. PrISM will also continually scan the field to identify critical gaps in equity-focused implementation research in order to help prioritize COBRE efforts. Aim 4. Collaborate with the Administrative Core to evaluate PrISM performance. The PrISM core addresses a previously unmet need at the University of Kansas Medical Center for an integrated team focused on implementation science. The PrISM Core will increase institutional and regional capacity to conduct high quality implementation research, will make research projects more pragmatic, and as a result will increase the COBRE’s potential for sustained and widespread impact on the field.