Scientific Leadership Group Core

项目总结 青少年医学艾滋病毒/艾滋病干预试验网络(ATN)在美国国立卫生研究院- 通过将科学和临床研究人员与必要的知识和 设计和实施跨学科、适合发展的预防战略的经验 美国的艾滋病毒携带者和高危青年。经验丰富、多学科、有远见的人 需要科学领导小组(SLG)，他们准备好发展、完善和支持既有的 以及正在出现的影响国内青年中艾滋病毒流行的ATN科学议程。无缝连接 在所有层面上，协作都是必不可少的，期望并要求投资于 应对青少年艾滋病毒预防和预防领域的重大挑战和机遇 关爱研究。高效和有效的沟通策略，以实现高影响力的研究义务 ATN SLG与科学领导中心(SLC)、统计和数据管理之间的协同作用 核心(SDMC)、运营和协作中心(OCC)、研究项目团队、现场联合体 以及NIH和行业合作伙伴。与SLC、SDMC、OCC和NIH合作的SLG准备就绪 执行ATN中的独特使命、优势和专业知识，找出ATN中的差距 研究组合，并形成额外的战略合作伙伴关系，以确保ATN对HIGH做出快速反应 优先和紧急研究领域。鉴于ATN的广泛议程，我们制定了一个强有力的、 跨学科特别工作组，包括与结束艾滋病毒流行有关的所有领域的世界专家，其中包括 美国的青少年。该小组由具有不同专业知识和经验的调查人员组成，包括 在种族/族裔、性别和性别认同、艾滋病毒状况、地域、纪律和培训方面的多样性。 根据多年的集体经验，Hightow-Weidman博士和Hosek博士将提供必要的 领导和基础设施，以支持SLG制定和完善ATN的研究议程，召开 工作组根据需要确定新兴研究项目的优先顺序，高效地管理临床研究的发展 方案、实施和完成临床试验，并确保及时发布和传达结果。 Hightow-Weidman博士和Hosek博士的目标是使用一种方法来管理SLG，通过 数十年的ATN和临床试验经验，将通过以下方式促进创新和有效性 灵活性，所有SLG团队成员之间的开放沟通，相互尊重，集体解决问题，以及 共同承担责任。SLG是通过围绕六个领域组织的领导团队进行配置的：生物医学 采购产品治疗，合并症和混合感染，实验室，诊断和移动技术，机构， 组织和策略、公平性、包容性和参与性，以及风险和弹性，并由 生物伦理委员会。这些内容领域涵盖了真正促进 多学科研究和翻译结果，以确保ATN最大限度地发挥临床和政策影响。

PROJECT SUMMARY The Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) fills a unique role among the NIH- funded networks by bringing together scientific and clinical investigators with the requisite knowledge and experience to design and implement interdisciplinary, developmentally appropriate prevention strategies for youth living with HIV and those at-risk in the United States (US). An experienced, multidisciplinary, and visionary Scientific Leadership Group (SLG) is needed who is poised to develop, refine, and support both an established and emerging ATN scientific agenda that impacts the HIV epidemic among youth domestically. Seamless collaboration will be essential at all levels, expecting and requiring innovation from investigators invested in addressing the significant challenges and seizing opportunities within the field of adolescent HIV prevention and care research. Efficient and effective communication strategies to accomplish high-impact research obligates synergies between the ATN SLG and Scientific Leadership Center (SLC), the Statistical and Data Management Core (SDMC), the Operations and Collaborations Center (OCC), the Research Project teams, Site Consortiums and NIH and industry partners. The SLG, working collaboratively with the SLC, SDMC, OCC and NIH is poised to actuate the unique mission, strengths, and expertise housed within the ATN, to identify gaps in the ATN research portfolio, and to form additional strategic partnerships that ensure the ATN’s swift response to high priority and emergent research areas. Given the broad ATN agenda, we have formulated a strong, interdisciplinary SLG which includes the world’s experts in all areas relevant to ending the HIV epidemic among adolescents in the US. This team consists of investigators with diverse expertise and experiences, including diversity in terms of race/ethnicity, sexual and gender identity, HIV-status, geography, discipline, and training. Building upon years of collective experience, Drs. Hightow-Weidman and Hosek will provide the necessary leadership and infrastructure to support the SLG to develop and refine the research agenda of the ATN, convene working groups as needed, prioritize emerging research projects, efficiently manage the development of clinical protocols, implement, and complete clinical trials and ensure timely publication and communication of results. Drs. Hightow-Weidman and Hosek aim to use an approach toward management of the SLG, honed through decades of prior ATN and clinical trials experiences, that will foster innovation and effectiveness through flexibility, open communication between all SLG team members, mutual respect, collective problem solving, and shared accountability. The SLG is configured through Leadership Teams organized around six areas: Biomedical Therapeutics, Comorbidities and Coinfections, Laboratory, Diagnostics and Mobile Technologies, Institutions, Organizations and Policy, Equity, Inclusion, and Engagement, and Risk and Resilience, and supported by a Bioethics Committee. These content areas encompass the areas of focus required to truly catalyze multidisciplinary research and translate the findings to ensure maximum clinical and policy impact by the ATN.