Bioinformatics Advanced Technology Platform (BAT Plat)

该项目将在Analytics Engines大数据平台上构建生物信息学管道，实现：诊断/伴随诊断重新定位，靶点选择，数据驱动的药物发现，数据驱动的药物重新定位和临床前模型系统对齐。这是通过推动生物信息学管道从特定的研究驱动环境转化为工业化临床流程来实现的。为了实现这一目标，管道需要完全可追溯、可重复和可扩展。提供可扩展存储和计算的高级技术已经可用，该提案解决了将生物信息学管道映射到这些技术的挑战。

This project will build a bioinformatics pipeline on top of the Analytics Engines big data platform enabling:diagnostic/companion diagnostic repositioning, target selection, data-driven drug discovery, data-driven drugrepositioning and pre-clinicial model system alignment.This is enabled by driving the translation of bioinformatics pipelines from ad-hoc, research-drivenenvironments into industrialised clinical processes. In order to achieve this aim, pipelines need to be fullytraceable, repeatable and scalable. Enterprise-grade technologies offering scalable storage and computationare already available, this proposal addresses the challenge of mapping bioinformatics pipelines to thesetechnologies.