GLAUCOMA DETECTION BY SCANNING LASER POLARIMETRY

一种新的技术--扫描激光偏振法将被用于测量 视网膜神经纤维层的绝对厚度以检测 青光眼和其他视神经疾病造成的早期损害。这项新测试 是基于平行的偏振特性，形式- 双折射神经纤维，可以通过未扩张的瞳孔施加。 已经设计了一种临床仪器，可以测量视网膜 视网膜上超过65,000个位置的神经纤维层厚度约为0.7 几秒钟。拟议的研究将通过比较来验证这项技术 用这台新仪器测量的已知性质 人视网膜神经纤维层和其他常规方法 诊断青光眼。这项研究的长期目标是发展 一种快速、方便、客观的筛查工具，用于早期检测和 青光眼的准确随访。 拟议的商业应用：这项研究可能会导致 开发灵敏、易于使用、快速(不到1秒)和 方便(无散瞳)试验早期诊断青光眼 目前是可能的。

A new technology, scanning laser polarimetry, will be employed to measure absolute thickness of the retinal nerve fiber layer in order to detect early damage from glaucoma and other optic neuropathies. This new test is based on the polarization properties of the parallel, form- birefringent nerve fibers and can be applied through the undilated pupil. A clinical instrument has been designed that allows to measure retinal nerve fiber layer thickness at over 65,000 retinal locations in about .7 seconds. The proposed research will validate this technology by comparing the measurements with this new instrument to known properties of the human retinal nerve fiber layer and other, conventional methods of diagnosing glaucoma. The long-term goal of this research is to develop a rapid, convenient, objective screening tool for early detection and accurate follow-up of glaucoma. PROPOSED COMMERCIAL APPLICATION: Potentially, this research will lead to the development of a sensitive, easy-to-use, rapid (under 1 second), and convenient (no pupil dilation) test to diagnoses glaucoma earlier than currently possible.