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ASP--A HIGH RESOLUTION TOMOGRAPH FOR SMALL ANIMALS

ASP--A HIGH RESOLUTION TOMOGRAPH FOR SMALL ANIMALS
ASP--小动物高分辨率断层扫描仪
批准号：
2102103
负责人：
WILLIAM L ROGERS
金额：
$17.62万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
1993
资助国家：
美国
项目状态：
已结题
起止时间：
1993-09-01 至 1996-08-31
来源：
https://reporter.nih.gov/project-details/2102103
关键词：
biomedical equipment development single photon emission computed tomography

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中文摘要
翻译
这项研究的长期目标是开发仪器和
英文摘要
The long-term aim of this research is to develop instrumentation and techniques for quantification in vivo of radioisotope localization in small animals in order to accelerate and simplify the design and evaluation of new radiopharmaceuticals. Animal SPRINT (ASP) is a high-resolution single-photon ring tomograph modeled after SPRINT but specifically designed for imaging 99mTc, 123I, and 131I in mice and rats with millimeter resolution. It is also capable of imaging larger animals such as primates and dogs at reduced resolution. Support is requested in this proposal to complete the final assembly of ASP, to characterize instrument performance, carry out verification tests with phantoms, and to assimilate the tomograph into routine use in our radiopharmaceutical biodistribution laboratory. This instrument will also be used in a separate research project to validate image reconstruction and estimation algorithms now under development using phantoms and small animals.
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ASP--A HIGH RESOLUTION TOMOGRAPH FOR SMALL ANIMALS
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