Improving bovine in vitro embryo production through follicular flushing and next generation embryo culture

“与养牛相关的技术正在取得重大进展，这些技术旨在提高生产效率、动物健康和福利，同时最大限度地减少对环境的影响。这些进步的部分原因是全球对牛奶和牛肉需求的增加，以及公众希望以可持续的方式实现这一目标。该项目旨在开发体外胚胎生产作为促进增强遗传改良的工具。具体来说，它将制造新的设备，以便在每个供体-奶牛周期（即通过卵巢-卵泡冲洗）中回收更多的卵母细胞（卵子），并为实验室内的胚胎培养创造新一代改进的培养基。总的来说，这些技术创新将提高胚胎生产效率，并导致移植后更高的妊娠率。反过来，这将导致只从最好的奶牛中繁殖，从而提高遗传改良的速度。牛饲养者渴望参与和利用这项技术，以改善牛群的健康、生产力和效率。这将使农民能够以更高的精度生产和饲养更适合其农业系统的动物。反过来，这将减少对动物饲料、化肥和农药等资源的需求，并减少动物粪便和温室气体排放。”

"Significant advances are being made in technologies associated with cattle breeding that seek to improve production efficiency, animal health and welfare whilst minimising environmental impact. These advances are motivated, in part, by the increased global demand for milk and beef, and a public desire that this is achieved in a sustainable manner. This project seeks to develop in vitro embryo production as a tool to facilitate enhanced genetic improvement. Specifically, it will manufacture new equipment to recover more oocytes (eggs) per donor-cow cycle (i.e. via ovarian-follicular flushing) and to create a new generation of improved media for the culture of embryos within the laboratory. Collectively, these technical innovations will increase embryo production efficiency and lead to higher pregnancy rates following transfer. This, in turn, will lead to increased rates of genetic improvement by breeding from only the best cows.Cattle breeders are eager to engage with and utilise this technology in order to improve the health, productivity and efficiency of their herds. This will enable farmers to produce and rear animals more suited to their farming system with greater precision. This will, in turn, reduce demand for resources such as animal feed, fertilisers and pesticides, and a reduction in animal waste and greenhouse gas emissions."