MATERNAL/FETAL HEMODYNAMICS RESPONSES TO EXERCISE

妇女越来越多地参与劳动大军和身体健康 已经要求对怀孕期间的锻炼进行重点研究。目前， 科学文献仅限于描述清楚和具体。 运动指南促进产妇健康，同时最大限度地减少胎儿 风险。现行的孕妇运动指南含糊不清。 这是最好的，也许没有科学依据。 拟议方案的重点是检查产妇和胎儿 医学上可接受的急性、非急性水平的血液动力学反应 负重运动。这个为期三年的计划的主要目标是 是提高候选人在以下领域的知识和研究技能 运动和怀孕，通过强化训练和广泛的指导。 建议研究的主要目的是：1)纵向评估 运动中母婴血流动力学反应；2)确定 运动强度与子宫动脉血流变化的关系 和脐动脉血流变化，同时监测胎儿安全；以及 3)评估怀孕期间运动的安全限度，根据 以产妇心率和体力消耗评分为指标。 这项实验研究将采用重复测量设计， 健康、不吸烟、怀孕的志愿者样本(n=45)。母心 心率、RPE、心输出量、每搏量、动脉压、子宫 动脉血流量和脐动脉血流量将在 不同孕期和运动强度。运动测试 将使用不连续的、症状受限的方案进行。这个 这项研究最终将有助于制定明确锻炼指南 对于健康的孕妇来说，同时加强候选人在 这片区域。

The growing participation by women in the workforce and physical fitness has mandated a focused study of exercise during pregnancy. Currently, the scientific literature is limited in delineating clear and specific exercise guidelines for promoting maternal health while minimizing fetal risk. The existing exercise guidelines for pregnant women are equivocal at best and perhaps without scientific basis. The focus of the proposed program is to examine maternal and fetal hemodynamic repercussions of medically accepted levels of acute, non- weight-bearing exercise. The primary objective of this three-year program is to advance the candidate's knowledge and research skills in the area of exercise and pregnancy, by intensive training and extensive mentorship. The major aims of the proposed study are: 1) To assess longitudinally the maternal-fetal hemodynamic repercussions during exercise; 2) to define the relationships among exercise intensity, uterine artery blood flow change, and umbilical artery blood flow change, while monitoring fetal safety; and 3) to assess the safety limits of exercise throughout gestation, according to the indices of maternal heart rate and Rating of Perceived Exertion. This experimental study will employ a repeated-measures design with a sample of healthy, non-smoking, pregnant volunteers (n=45). Maternal heart rate, RPE, cardiac output, stroke volume, arterial pressure, uterine artery blood flow, and umbilical artery blood flow will be measured at different gestation periods and exercise intensities. The exercise tests will be conducted with a discontinuous, symptom-limited protocol. The study will ultimately aide development of unequivocal exercise guidelines for healthy pregnant women, while strengthening the candidate's career in this area.