CCD AREA DETECTOR RESEARCH RESOURCE

我们建议创建和运营一个研究资源，用于开发 蛋白质结晶学的面积检测技术。这项技术将 可应用于两个同步加速器X射线源，如Argonne的Advanced 光子源和实验室X射线发生器。我们目前的项目是 利用电荷耦合器件开发积分型面阵探测器 将协调和结合起来，允许更快、更有序 这一关键硬件的开发。先进的探测器系统将是 开发了结合了CCD芯片的最新技术进步的产品， 快速的计算机、快速的磁盘存储器和光纤。这些探测器将 空间分辨率高，动态范围大，面积大，高 高效率和高读出速度。中西部地区探测器设施 (M.A.D.)将在阿贡建立常规X射线源 探测器的应用，并作为研究资源纳入研究资源 为社会服务。最后，我们将开发一个探测器中心 软件开发，这是这个不断增长的领域迫切需要的。我们 将开发解决三个问题的计算机程序：快速数据 转移、快速加工的海量单色 由同步加速器探测器提供的衍射数据，以及 劳厄衍射图的采集与处理。

We propose to create and operate a research resource for the development of area detector technology for protein crystallography. This technology will be applied to both synchrotron x-ray sources, such as Argonne's Advanced Photon Source, and laboratory x-ray generators. Our present projects to develop integrating area detectors using the charge-coupled device (CCD) will be coordinated and combined, permitting more rapid and more orderly development of this crucial hardware. Advanced detector systems will be developed which incorporate recent technological advances in CCD chips, fast computers, fast disk memories, and fiber optics. These detectors will have high spatial resolution, large dynamic range, large areas, high efficiency, and high readout speeds. The Midwest Area Detector Facility (M.A.D.) will be established at Argonne for conventional x-ray source applications of detectors and incorporated into the Research Resource as a service to the community. Finally, we will develop a center for detector software development, which is desperately needed in this growing field. We will develop computer programs that address three problems: rapid data transfer, rapid processing of the vast quantities of monochromatic diffraction data made available by synchrotron-based detectors, and the collection and processing of Laue diffraction images.