AEROSOL SAMPLER PERFORMANCE CHARACTERISTICS

拟议项目的目的是提供一种更好的科学 开发适用于健康的新型取样器的框架- 工作场所气溶胶的相关测量。新的粒度选择 标准，这些标准有望成为新的工业卫生的基础 标准，目前正在刺激对取样器的批判性检查 使用中(根据这些标准)和开发新的 设备。 当前发展和发展的一个主要限制因素 这类仪器的设计在于对其缺乏足够的认识 实际抽样过程本身，特别是影响 将空气中的颗粒物吸入采样的效率 从外面的环境空气中隔离设备。其结果是， 符合预期性能特征的实用仪器具有这样的特点 这在很大程度上是经验性的。因此，拟议的项目包括 对一些突出的相关科学问题的科学探究 问题。目标将是产生量化工作 实用粒度选择未来设计指南 采样设备。 这项工作本身将涉及以实验室为基础的实验 研究，使用已在广泛建立的技术 首席调查员参与的以前的研究 在过去的15年里一直联系在一起。这将由物理和 统计建模的目的是能够推广 为取得实际成果而获得的科学知识。 鉴于目前正在进行的 关于工人评估方法的国际协调 暴露在气雾剂中。

The aim of the proposed project is to provide an improved scientific framework for developing new samplers suitable for use in the health- related measurement of workplace aerosols. New particle size-selective criteria, which are expected to form the basis of new industrial hygiene standards, are stimulating a critical examination of samplers, currently in use (in the light of those criteria) and the development of new devices. A major limiting factor in the current apprnach to the development and design of such instruments lies in the lack of sufficient understanding of the actual sampling process itself, in particular of the factors governing the efficiency with which airborne particles are drawn into the sampling device from the ambient air outside. As a result, the development of practical instruments matching desired performance characteristics has so far been largely empirical. The proposed project therefore comprises a scientific enquiry into some of the outstanding relevant scientific questions. The objective will be to generate quantitative working guidelines for the future design of practical particle size-selective sampling devices. The conduct of the work itself will involve laboratory-based experimental research, using techniques which have been established in extensive previous research with which the principal investigator has been associated for the past 15 years. This will be backed up by physical and statistical modeling aimed at enabling the generalization of the scientific knowledge gained towards practical outcomes. The project is particularly timely in view of the current move towards international harmonization on methodology for the assessment of worker exposures to aerosols.