CEREBRAL MRI TO THE ATHEROSCLEROSIS RISK

本合同的目的是提供阅读服务 中心解读脑磁共振图像（MRI） 在流行病学研究中， 中年人心血管疾病的发生率 社区动脉粥样硬化风险研究（ARIC）。“MRI 阅读中心将协助制定绩效方案 在两个ARIC现场中心对2,000名参与者进行了脑部MRI检查， 位于杰克逊，女士和福赛斯县，北卡罗来纳州，并将执行 测量和解释这些图像在一个标准化的， 可复制的方式。 社区动脉粥样硬化风险（ARIC），一项心血管疾病研究 美国四个社区的男性、女性、黑人和白人中的疾病， 有两个主要目标：（1）调查与 动脉粥样硬化和临床心血管疾病的发病率， 和（2）测量冠心病（CHD）的发生率和趋势， 将它们与社区水平的风险因素、医疗保健和 动脉粥样硬化 在操作上，该研究包括监测 四个社区35-74岁居民冠心病患病率 对4，000名年龄在45-64岁之间的人进行了首次体检， （1987-1990年）选出代表每个社区的人。 的 研究社区有福赛斯县，北卡罗来纳州，杰克逊， 密西西比、明尼阿波利斯郊区、明尼苏达州和华盛顿县， 马里兰州。

The purpose of this contract is to provide the services of a reading center to interpret cerebral magnetic resonance images (MRI) performed in the epidemiological research study of the major factors contributing to the occurrence of cardiovascular disease in middle-aged adults entitled "Atherosclerosis Risk in Communities Study (ARIC)." The MRI Reading Center will assist in protocol development for the performance of cerebral MRI on 2,000 participants at two of the ARIC Field Centers located in Jackson, Ms and Forsyth County, NC; and will perform measurements and interpretations of these images in a standardized and reproducible manner. Atherosclerosis Risk in Communities (ARIC), a study of cardiovascular diseases in four U.S. communities among men, women, blacks and whites, has two primary objectives: (1) to investigate factors associated with both atherosclerosis and incidence of clinical cardiovascular diseases, and (2) to measure coronary heart disease (CHD) occurrence and trends and relate them to community levels of risk factors, medical care and atherosclerosis. Operationally, the study includes both surveillance for coronary disease among all residents aged 35-74 of the four communities and follow-up of cohorts of 4,000 persons aged 45-64 at first examination (which occurred in 1987-1990) selected to represent each community. The study communities are Forsyth County, North Carolina, Jackson, Mississippi, suburbs of Minneapolis, Minnesota, and Washington County, Maryland.