THREE DIMENSIONAL CT ANGIOGRAPHY

描述(改编自申请者摘要)：计算机断层扫描 (CT)血管造影术是一种对血管系统进行成像的方法 将创新的图像处理与新型滑环CT的使用相结合 扫描仪。这种方法允许快速获取大型 外周动脉相期间的CT数据量 静脉注射造影剂。拟议项目的目标 将是开发利用这一点的算法和技术 体积扫描CT技术生成三维CT血管成像 这可能会取代更昂贵和更具侵入性的动脉内介入治疗 腹部血管造影术的特殊应用。技术上的 开发将包括计算机算法，用于产生两个 来自3-D CT数据的二维(2-D)血管成像，对比剂计时 技术，最大限度地减少运动和推注计时产生的伪影 不准确性，以及用于分割的图像处理策略 包含骨骼和软组织的体积中的复杂血管结构 组织。将进行临床研究以评估诊断 肾动脉狭窄和腹壁狭窄的诊断准确性 主动脉瘤。在这一项目成功完成后， 申请者预计，这种方法将是一种更低的成本、更低的成本 风险替代诊断动脉造影术。

DESCRIPTION (Adapted from Applicant's Abstract): Computed Tomography (CT) Angiography is a method for imaging the vascular system that combines innovative image processing with the use of new slip-ring CT scanners. This method allows for the rapid acquisition of large volumes of CT data during the arterial phase of a peripheral intravenous contrast injection. The goals of the proposed project would be to develop the algorithms and techniques that exploit this volume-scan CT technology to produce three-dimensional CT angiograms that could substitute for more costly and invasive intra-arterial angiograms in specific applications within the abdomen. The technical developments would include computer algorithms for production of two dimensional (2-D) angiograms from 3-D CT data, contrast bolus timing techniques, minimization of artifacts from motion and bolus timing inaccuracies, and image processing strategies for segmentation of complex vascular structures from volumes containing bones and soft tissue. Clinical studies would be conducted to assess the diagnostic accuracy of the method in renal artery stenosis and in abdominal aortic aneurysms. Upon the successful completion of this project, the applicants projected that the method would be a lower cost, lower risk alternative to diagnostic arteriography.