EXPERIMENTAL AND THEORETICAL STUDY OF DHFR KINETICS

我选择了本科维奇实验室的博士后职位， 运用我以前在理论生物物理学和化学物理学方面的训练 当前感兴趣的生物系统。 我选择DHFR是因为 丰富的实验信息，因为过程相关 的反应动力学是易于处理的一个组合的实验和 理论方法。 本科维奇博士是酶促反应研究的领导者 反应，提供了重要的洞察动力学机制 对于DHFR，催化抗体，单加氧酶，聚合酶和其他 内切酶

I have selected a postdoctoral position in the Benkovic Lab in order to apply my previous training in theoretical biophysics and chemical physics to biological systems of current interest. I chose DHFR because of the wealth of experimental information available, and because processes related to the reaction dynamics are tractable by a combined experimental and theoretical approach. Dr. Benkovic is a leader in the study of enzymatic reactions, having provided significant insight on the kinetic mechanisms for DHFR, catalytic antibodies, monoxygenases, polymerases and other enzymes.