EPIDEMIOLOGY OF PERSONALITY DISORDERS

描述(改编自申请人的摘要)：流行性感冒的流行病学 人格障碍包括对其特征、患病率的研究 和分布，以及与精神病理学的联系。这是最好的 通过从普通人群中抽取样本进行了调查。900人的队列 个人，最初是东部居民的概率样本 巴尔的摩在1981年年满18周岁，将被研究。这样做的目的是 研究内容如下：(1)评估人格障碍的潜在结构 结构；(2)估计11个DSM-IV人格的患病率 并确定人格障碍的分布维度； (3)评估人格障碍与具体人格障碍的关系 轴心I条件；以及(4)调查社会成本和后果 人格病理学的研究。 这些受试者将由精神科医生使用扫描进行检查。人格 评估将以多种测量方式进行 包括结构化人格障碍访谈(PDE)、临床 由精神病学家进行评估，使用PDE进行线人评估，以及两个 测量不同个性的自填式问卷 维度(NEO-PI和TCI)。将使用各种分析技术， 包括对权重的估计，以允许根据年龄进行减员调整， 性和种族。 当前的方案通过利用跟踪来最大限度地降低成本 和对非洲经委会后续研究的诊断性评价 有资金支持。它提供了一个不同寻常的机会来深入了解 人格障碍；其诊断、人口比率和分布， 以及进程和后果。

DESCRIPTION (Adapted from applicant's abstract): The epidemiology of personality disorders includes study of their characteristics, prevalence and distribution, and association with psychopathology. It is best conducted with a sample drawn from the general population. A cohort of 900 individuals, originally a probability sample of residents of Eastern Baltimore over 18 years of age in 1981, will be studied. The goals of this research are: (1) to assess the latent structure of personality disorder constructs; (2) to estimate the prevalence of eleven DSM-IV personality disorders and determine the distribution of personality disorder dimensions; (3) to evaluate the relationship between personality disorders and specific Axis I conditions; and (4) to investigate the social costs and consequences of personality pathology. The subjects will be examined by psychiatrists using the SCAN. Personality assessment will be conducted with multiple modalities of measurement including a structured personality disorder interview (PDE), clinical evaluation by a psychiatrist, informant assessment using the PDE, and two self-administered questionnaires which measure different personality dimensions (NEO-PI and TCI). A variety of analytic techniques will be used, including estimation of weights to permit adjustment for attrition by age, sex and race. This current proposal minimizes costs by taking advantages of the tracing and diagnostic evaluations of the ECA follow-up study which is already funded. It provides an unusual opportunity to develop insights into personality disorders; their diagnosis, population rates and distribution, and course and consequences.