CHILDHOOD PREDICTORS OF ALCOHOLISM AND VIOLENCE

以前对酒精中毒和暴力的大多数心理生理学研究是 由于它是横截面的，而且是纵向的，所以受到限制。至 针对文献中的这一关键问题，我们建议进行 酒精中毒和反社会行为的前瞻性、纵向研究。 两个重要的假设将被检验：1)非反社会 酗酒者表现出自主神经和中枢神经系统过度兴奋2) 反社会酗酒者表现出自主和中枢系统 缺乏觉醒。 为了检验这些假设，分析将在以下背景下进行 毛里求斯纵向项目的执行情况。皮肤电导率和皮肤电导率的测量 心率唤醒和定向是在1972年通过一组 1795名3岁的毛里求斯儿童。男性和女性是平等的 代表，而印度教徒、穆斯林、克里奥尔人和中国人 在样本中的比例与他们在岛上的代表性。在… 在11岁时，这些测量重复进行，而关于 同时采集静息脑电和事件相关电位。在 目前，我们建议对所有主题进行诊断性访谈 他们届时将年满28岁，以确定他们的酗酒情况 诊断。有关所有DSM-IV轴I和轴II紊乱的信息将 也可以使用SCID获得。此外，自我报告和 反社会和暴力行为的官方衡量标准，即 目前正在由NIMH资助的一项研究中收集，将可用 在所有主题上。这些诊断广告反社会行为的结果 然后，测量将与所获得的心理生理测量相关 在3岁和11岁时。这项研究的结果将对 了解酗酒和反社会行为的发展。到期 对早期采取的心理生理措施的合理收集 童年在一个广泛的队列中，其中包括女性和四个种族 团体，人们认为这个项目提供了一个独特的机会 评估酒精中毒的早期心理生理危险因素 暴力，并探讨族裔和性别的影响。这样的研究已经 反过来，有可能解决最近四个月提出的一些问题 与青年、暴力、妇女和少数群体有关的酗酒问题论坛。

Most previous psychophysiological research on alcoholism and violence is limited by the fact that it is cross-sectional, and longitudinal. To address this critical gas in the literature, we propose to conduct a prospective, longitudinal study of alcoholism and antisocial behavior. Two overarching hypotheses will be tested: 1) that non-antisocial alcoholics show autonomic and central nervous system overarousal and 2) that antisocial alcoholics show autonomic and central system underarousal. To test these hypotheses, analyses will be conducted within the context of the Mauritius longitudinal project. Measures of skin conductance and heart rate arousal and orienting were acquired in 1972 on a cohort of 1,795 three-year-old Mauritian children. Males and females are equally represented, while Hindus, Muslims, Creoles, and Chinese are contained in the sample in proportion to their representation on the island. At age 11 years, these measures were repeated, while additional data on resting EEG and event-related potentials were also collected. In the present, we propose to conduct diagnostic interviews on all the subjects who will then be aged 28 years in order to ascertain their alcoholism diagnoses. Information on all DSM-IV Axis I and Axis II disorders will also be obtained using the SCID. In addition, both self-report and official measures of antisocial, and violent behavior, which are currently being collected in a study funded by NIMH, will be available on all subjects. These diagnostic ad antisocial behavior outcome measures will then be related to psychophysiological measures obtained at ages 3 and 11 years. Results of this study will have implications for understanding the development of alcoholism and antisocial behavior. Due to the sound collection of psychophysiological measures taken in early childhood on an extensive cohort which includes females and four ethnic groups, it is felt that this project offers a unique opportunity to assess early psychophysiological risk factors for alcoholism and violence, and to explore ethnic and gender effects. Such research has in turn the potential to address some of the issues raised in four recent RFAs on alcoholism pertaining to youth, violence, women, and minorities.