A cellular hub for the organisation of T cell priming

该项目旨在通过利用先进的活体成像来描述启动免疫反应所涉及的细胞相互作用。脊椎动物的获得性免疫功能是通过免疫细胞通过与其他免疫细胞的复杂相互作用获得信号来发挥作用的，但这种交换很难观察和定义。该项目期望为支持有效的细胞介导免疫反应的机制提供洞察力。预期的结果是产生关于免疫反应的基本新知识，并提高研究免疫系统的能力。这可能有利于未来开发新的疫苗和疗法来改善健康。

This project aims to delineate the cellular interactions involved in the initiation of immune responses by utilising advanced in vivo imaging. Adaptive immunity in vertebrates functions via the acquisition of signals by immune cells via complex interactions with other immune cells, yet these exchanges are difficult to observe and define. This project expects to provide insights into the mechanisms that underpin effective cell-mediated immune responses. The expected outcomes are to generate fundamental new knowledge about immune responses and enhance capacity to study the immune system. This could benefit future development of new vaccines and therapies to improve health.