A 3-photon imaging system for deep live imaging

用于深度实时成像的三光子成像系统

• 批准号: LE210100001
• 负责人: Prof Scott Mueller
• 金额: $ 58.35万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Infrastructure, Equipment and Facilities
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-07-28 至 2022-07-28
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LE210100001
• 关键词: photon; imaging; system; deep; live

This project aims to establish Australia’s first 3-photon microscope system with adaptive optics for deep intravital imaging. This advanced imaging system will enable researchers to investigate the biology of cells and tissue structures in a wide range of organs and engineered tissues, to a degree not possible with existing technology. This project will capitalise on advanced laser, microscope and adaptive optics technologies with the expected outcomes to include the generation of new knowledge of major biological systems, including the immune system and the nervous system. This will provide significant benefits to fundamental interdisciplinary research into immunology, infectious disease, neuroscience, mechanobiology and engineering.

该项目旨在建立澳大利亚第一个具有自适应光学的3光子显微镜系统，用于深度活体成像。这种先进的成像系统将使研究人员能够在广泛的器官和工程组织中研究细胞和组织结构的生物学，达到现有技术无法达到的程度。该项目将利用先进的激光，显微镜和自适应光学技术，预期成果包括产生主要生物系统的新知识，包括免疫系统和神经系统。这将为免疫学、传染病、神经科学、机械生物学和工程学的基础跨学科研究提供重大益处。