Formation of boundaries in the developing embryo

这个项目旨在破译发育中的胚胎中不同器官之间的边界是如何建立的。该项目旨在确定控制侧板中胚层形成的基因调控网络的组成部分，开发一个数学模型来解释这些区域是如何在该区域内形成的，并验证斑马鱼体内新的相互作用。该项目的预期结果是揭示我们身体部位的祖先是如何被指示在胚胎的正确时间和正确位置定位的。该项目应该会带来巨大的好处，例如扩大澳大利亚在跨学科科学方面的知识基础和研究能力。

This project aims to decipher how the boundaries between the different organs are established in the developing embryo. The project aims to identify the components of the gene regulatory network that controls lateral plate mesoderm formation, develop a mathematical model that can explain how the domains are formed within this region, and validate novel interactions in vivo in zebrafish. The expected outcome of the project is to reveal how the progenitors of our body parts are instructed to be positioned at the right time and at the right place in the embryo. This project should provide significant benefit such as the expansion of Australia's knowledge base and research capability in cross-disciplinary science.