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INTRATUMORAL/INTERSTITIAL THERAPY WITH HN-6600 IN REFRACOTRY GLIOBLASTOMA

INTRATUMORAL/INTERSTITIAL THERAPY WITH HN-6600 IN REFRACOTRY GLIOBLASTOMA
HN-6600 瘤内/间质治疗难治性胶质母细胞瘤
批准号：
6278900
负责人：
JEFFREY N BRUCE
金额：
$2.3万
依托单位：
COLUMBIA UNIVERSITY HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-12-01 至 1998-11-30
来源：
https://reporter.nih.gov/project-details/6278900
关键词：
antineoplastics catheterization cerebrovascular surgery chemical conjugate clinical research drug administration routes drug screening /evaluation glioblastoma multiforme human subject human therapy evaluation interstitial neoplasm /cancer chemotherapy neoplasm /cancer relapse /recurrence

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中文摘要
翻译
一种新的实验性治疗复发恶性脑肿瘤的方法已经 已经开发出一种名为靶向的新型抗癌药物 蛋白质毒素。这项研究是为了找出它是否可以安全使用和 对患有恶性脑瘤的患者有效。一台水泵就能 通过导管连续输注HN-66000 5至7天 会被手术安置在病人脑瘤的中心。
英文摘要
A new experimental treatment for recurrent malignant brain tumors has been developed that uses a new type of anticancer drug called a targeted protein toxin. This study is to find out if it can be used safely and effectively in patients with malignant brain tumors. A pump will continuously infuse HN-66000 for 5 to 7 days through a catheter that will be surgically placed into the center of the patient's brain tumor.
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会议论文
Single Cell Analysis of the Infiltrative Margins of Glioblastoma and Post Treatment Recurrence
Single cell analysis of the infiltrative margins of glioblastoma and post-treatment recurrence
Single cell analysis of the infiltrative margins of glioblastoma and post-treatment recurrence
CHRONIC CONVECTION ENHANCED DELIVERY (CED) OF TOPOTECAN FOR GLIOBLASTOMA
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