DEVELOPMENT GRANTS IN PROSTATE CANCER

弗吉尼亚大学前列腺癌发展项目 代表一个多学科团队，专注于转化研究 旨在通过以下方法降低前列腺癌的发病率和死亡率： 改善预防、诊断和治疗。该应用程序集成了 肿瘤细胞生物学家和临床研究人员组成一个团队， 详细研究生长控制机制的能力， 这种肿瘤的转移潜力，并制定治疗策略， 这两种现象。该计划由查尔斯·迈尔斯博士指导， 前列腺药物发现的权威，包括五个试点项目， 请求为新调查员提供支助，并进行规划和评价 成分规划补助金包括一个内部咨询委员会， 一批优秀的外部顾问。项目将审查 EGF受体的功能，EGF的作用， ras信号通路的功能和磷脂酶A2的作用 以及肿瘤诱导免疫抑制的机制。这些项目 解决肿瘤细胞生物学方面的关键侵入性和生长 控制新的调查资金将用于鼓励初级和 已建立的研究人员加入我们的前列腺研究团队。

The University of Virginia Development Program in Prostate Cancer represents a multidisciplinary team focused on translational research aimed at reducing the incidence and mortality of prostate cancer through improved prevention, diagnosis and treatment. This application integrates tumor cell biologists and clinical investigators into a team with the ability to examine in detail the mechanisms of growth control and metastatic potential of this tumor and develop therapeutic strategies to block both phenomenon. This program is directed by Dr. Charles Myers, an authority in prostate drug discovery and includes five pilot projects, a request for support of new investigators and a planning and evaluation component. The Planning Grant includes an internal advisory committee, and a group of outstanding external consultants. Projects will examine adhesion-directed signalling, the function of the EGF receptor, the function of the ras signalling pathway and the role of phospholipase A2 and the mechanism of tumor-induced immunosuppression. These projects address aspects of tumor cell biology critical to invasiveness and growth control. The new investigator funds will be used to encourage junior and established investigators to join our team of prostate investigators.