The Neural Bases of Decision-Making

认知和情感过程的平稳整合是日常决策所必需的。这种综合能力的功能障碍伴随着痴呆症、神经退行性疾病和严重的精神疾病。该项目试图了解正常决策中这种整合的神经基础，使用尖端的行为、细胞、分子和遗传工具绘制神经系统、电路和细胞过程图，控制目标导向行动的选择、评估和选择。如果继续练习，这样的行为可能会转变为相对僵化的习惯。因此，这个项目旨在研究调节这种转变的神经过程，以及行为和习惯在正常决策中是如何相互作用的。

The smooth integration of cognitive and emotional processes is necessary for everyday decisions. Dysfunction in this integrative capacity accompanies dementia, neurodegenerative conditions and major psychiatric disorders. This project seeks to understand the neural bases of this integration in normal decision-making using cutting edge behavioural, cellular, molecular and genetic tools to map the neural system, circuit and cellular processes controlling the selection, evaluation and choice of goal-directed actions. Such actions can, with continued practice, transition into relatively inflexible habits. Thus, this project aims to investigate the neural processes that mediate this transition and how actions and habits interact in normal decision-making.