1999 FASEB CONFERENCE--PROTEIN KINASES & PHOSPHORYLATION

美国实验生物学学会联合会（FASEB）关于蛋白激酶和磷酸化的会议将于1999年7月24日至7月29日在科罗拉多州斯诺马斯村举行。这将是自1983年首次会议以来，第九次每两年举行一次的会议。本申请为会议的运作寻求部分支持。蛋白激酶和磷酸化领域的研究是研究信号转导途径和细胞过程调控的重要组成部分。在过去的两年里，我们对这些酶在结构和细胞水平上的功能的理解有了巨大的进步。特别是在理解蛋白激酶在控制程序性细胞死亡（凋亡）、调节神经元离子通道活性以及通过激酶和磷酸酶信号支架与选定的靶底物的定位协调磷酸化事件中的作用方面取得了进展。本次会议的目的是将研究人员聚集在一起，研究蛋白激酶生物学的这些和其他重要方面，为期五天的集中相互作用。与其他FASEB夏季会议一样，本次会议将从申请中选择250名与会者，包括工业界和学术界的代表。参与者将包括资深科学家、博士后和研究生。不断有来自不同学科的新研究人员进入这一领域，1999年的会议将对蛋白质激酶的遗传学、生物化学和细胞生物学的重点介绍和讨论非常重要。会议将由八届会议组成，每届会议都有一名讨论领导和至少六名发言人，从最近作出重要贡献的调查人员和提交的摘要中选出。这将有助于确保青年调查人员、妇女和少数民族成为主要参与者。此外，还将组织两次海报会议。在1997年的会议上，提交了120多张海报，每次两天，为科学交流提供了另一种重要形式。

The Federation of American Societies for Experimental Biology (FASEB) Conference on protein kinases and phosphorylation will be held from July 24th to July 29th 1999 in Snowmass Village, Colorado. This will be the ninth biannual conference on this subject since the inaugural meeting in 1983. This application seeks partial support for the operation of the conference. Research in the area of protein kinases and phosphorylation is an essential part of the investigation into signal transduction pathways and the regulation of cellular processes. Within the past two years there have been tremendous advances in our understanding of how these enzymes function at both the structural and cellular levels. In particular there has been progress in understanding the role of protein kinases in the control of program cell death (apoptosis), modulation of neuronal ion channel activity, and the coordination phosphorylation events though the localization of kinase and phosphatase signaling scaffolds with selected target substrates. The purpose of this conference is to bring together investigators studying these and other important aspects of protein kinases biology for a five day period of concentrated interaction. Like other FASEB Summer conferences, this meeting will select 250 participants from applications, including representatives from industry and academia. Participants will include senior scientists, postdoctorates and graduate students. There is a constant infusion of new researchers from various disciplines into this area and the 1999 conference will be important for a focused presentation and discussion of the genetics, biochemistry and cell biology of protein kineses. The Conference will consist of eight sessions, each with a discussion leader and at least six speakers, selected from investigators who have made important recent contributions and from submitted abstracts. This will help to ensure inclusion of young investigators, women and minorities as primary participants. In addition, two poster sessions will be organized. At the 1997 Conference, more than 120 posters were presented for two days each and provided another important format for scientific exchange.