ORGAN TRANSPLANTATION IN ANIMALS AND MAN

这是一份继续项目资助的申请。 基本 总体目标是：（a）分析和隔离临床问题 参与器官移植并精确记录临床实验室 相关性 (b)根据现有数据组织临床试验，以解决 临床问题。 (c)产生这些问题的实验解决方案， 最终可以应用于临床问题。 在这些目标中，有四个基本目标，在临床 我们所有的项目都是在移植的基础上进行的。 目标1： 防止宿主破坏器官。 这包括组织分型的问题， 匹配，和免疫抑制有关的排斥反应，以及问题， 复发性疾病 目的二：防止感染。 目标3：最大化 康复活动. 目标4：维持患者和器官处于最佳状态 移植前和移植期间。 这包括血液透析的问题， 器官回收和储存

This is an application for continuation of a program project grant. The basic overall objectives have been to: (a) Analyze and isolate the clinical problems involved in organ transplantation and precisely document clinical-laboratory correlations. (b) Organize clinical trials based on available data to solve clinical problems. (c) Generate experimental solutions to these problems which can ultimately be applied to the clinical problem. Within these objectives, there are four essential aims in clinical transplantation under which all our projects have been organized. Aim 1: To Prevent Organ Destruction by host. This includes problems of tissue typing, matching, and immunosuppression related to rejection as well as problems of recurrent disease. Aim 2: To Counteract Infection. Aim 3: To Maximize Rehabilitation. Aim 4: To Maintain Patient and Organ in Optimal Condition Prior to and During Transplantation. This includes problems of hemodialysis, organ retrieval, and storage.