CORE--LABORATORY CORE

实验室核心的作用将是提供设施和 最有效地协助基础和实验室研究人员的专业知识 与临床问题相关的研究。这将通过提供一个 四个实验室的核心，每个实验室都有一名经验丰富的基础科学家 协调员。此外，大学核心研究服务处将 提供标准实验室程序的日常支持和 大学集中研究设施将提供尖端的 设备和最先进的方法。核心将由以下人员执导 C.Squier博士，负责研究的助理院长兼道琼斯公司董事 在牙医学院。实验室协调员将 定期与局长和调查人员会面，就行为提供建议 以及研究的进展。这一概念将提供灵活的实验室 以最适合临床类型的方法提供支持 正在进行的研究。将为调查人员提供培训，由 提供正规课程和个人辅导。 将支持的研究将包括中心试点项目以及 将现有的独立资助项目扩展到与以下领域有关的领域 NIDR研究和行动计划的目标。在头两年， 这将代表3个试点项目，共同利用每个核心项目 实验室和联合使用的设施，以及独立的 利用其中三个核心实验室资助的项目。把这个放在一起 临床研究将为改善患者的生活质量做出重大贡献 老年患者和高危人群的口腔健康。

The role of the Laboratory Core will be to provide the facilities and expertise to most efficiently assist investigators in basic and laboratory studies related to clinical problems. This will be achieved by offering a Core of four laboratories each with an experienced basic scientist as a Coordinator. In addition, the Collegiate Core Research Services will provide routine support with standard laboratory procedures and the University Centralized Research Facilities will offer sophisticated equipment and state-of-the-art methodology. The Core will be directed by Dr. C. Squier, Assistant Dean for Research and Director of the Dows Institute at the College of Dentistry. The Laboratory Coordinators will meet regularly with the Director and investigators to advise on the conduct and progress of studies. This concept will provide flexible laboratory support with the methodology most appropriate to the type of clinical research being undertaken. Training will be offered to investigators by provision of both formal courses and by individual mentoring. The research to be supported will include Center Pilot Projects as well as extensions of existing independently funded projects into areas relevant to the aims of the NIDR Research and Action Program. In the first two years, this will represent 3 pilot projects together utilizing each of the core laboratories, and the joint use facilities, and extensions of independently funded projects utilizing three of the core laboratories. Together this clinical research will provide a significant contribution to improving the oral health of older patients and individuals at high risk.