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中文摘要
翻译
罗切斯特流行病学项目(REP)是一个独特的,以人口为基础的 数据资源包括完整的(不耐烦和门诊) 所有奥姆斯特德县,MN居民的医疗记录,为整个 在县内居住的时间。 我们的数据库现在覆盖了 基本上所有提供者都向县居民提供医疗服务 从1909年到现在,已经出版了565本书, 该系统是在1966年组织的(自上次竞争性比赛以来, 更新五年前)在无数的主题-许多有关的关键 国家重要的健康问题。 代表支持一个 来自马约和其他学术机构的大量调查人员 在美国和国外,使有效的行为成为可能, 由校外资助的冠心病,中风, 痴呆和其他神经系统疾病、癌症、糖尿病和其他 代谢性疾病、胃肠道疾病、骨质疏松症、关节炎, 和其他. 尽管马约诊所通过索引 诊断、外科手术和病理学记录在其自己的 记录在没有成本的这个项目,这是代表的责任 从非梅奥提供者那里收集诊断数据, 从所有护理来源获得信息,并使所有人都能获得 合格的研究人员进行描述性和分析性研究。 继续 需要支持来补充马约诊所的诊断指数, 数据来自奥姆斯特德医疗集团,奥姆斯特德社区医院和 奥姆斯特德及其周边地区的其他几个非梅奥医疗保健来源 并对所承担的组织任务进行了强化研究 罗切斯特流行病学项目的能力,并增加其 效率 所要求的资金必须(1)维持和继续增加 REP数据库的非梅奥部分,这使得完整的 基于人口的调查所需的病例确定和后续行动水平 在罗切斯特和奥姆斯特德县的研究,并形成了必要的核心, 在这一人群中的流行病学研究;(2)扩展我们的研究 通过形成新的实验室结果、诊断 (3)通过使用现代化的数据库, 关系数据库技术,用于开发全局文件(REP 医学档案),包含姓名的纵向记录, 身份证号码、住所、医疗护理时间, 住院、临床和病理诊断、手术和 诊断程序、实验室检查值、处方药,以及 与每一个登记在一个特定的 (4)提高后勤支援的效率 通过自动化许多程序的样本选择, 验证,并生成和跟踪后续通信, 并与国家死亡指数建立接口。
英文摘要
The Rochester Epidemiology Project (REP) is a unique, population-based data resource comprised of the complete (impatient and outpatient) medical records of all Olmsted County, MN residents for the entire duration of their residency in the County. Our data base now covers the medical care delivered by essentially all providers to County residents from 1909 through the present and has resulted in 565 publications since the system was organized in 1966 (and 212 since the last competitive renewal five years ago) on a myriad of topics--many relating to critical health issues of national importance. The REP supports the work of a large number of investigators from Mayo and other academic institutions in the United States and abroad and makes possible the efficient conduct of extramurally funded studies of coronary heart disease, stroke, dementia and other neurological conditions, cancer, diabetes and other metabolic diseases, gastrointestinal disorders, osteoporosis, arthritis, and other. Although Mayo Clinic contributes substantially by indexing the diagnoses, surgical procedures and pathology recorded in its own records at no cost to this project, it is the responsibility of the REP to collect the diagnostic data from non-Mayo providers, to integrate the information from all sources of care, and to make it accessible to all qualified investigators for descriptive and analytic studies. Continued support is needed to supplement the Mayo Clinic diagnostic index with data from the Olmsted Medical Group, the Olmsted Community Hospital and several other non-Mayo sources of medical care in and around Olmsted County and to undertake organizational tasks that enhance the research capabilities of the Rochester Epidemiology Project and increase its efficiency. The funds requested are required to (1) maintain and continue adding to the non-Mayo portion of the REP data base, which makes possible the full level of case ascertainment and follow-up required for population-based studies in Rochester and Olmsted County and forms the essential core for epidemiologic research in this population; (2) extend our research capabilities by forming new indexes for laboratory results, diagnostic procedures and medications; (3) modernize the data base by using relational data base technology to develop a global file (the REP Medical Profile) containing a longitudinal record of names, identification numbers, residences, episodes of medical care and hospitalization, clinical and pathological diagnoses, surgical and diagnostic procedures, laboratory values, prescription drugs, and linkages to the detailed data of each resident enrolled in a specific study or registry; and (4) enhance the efficiency of logistical support by automating many of the procedures for sample selection, for residency verification, and for generating and tracking follow-up correspondence, and by establishing an interface with the National Death Index.
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RISK FACTORS FOR FRACTURES AMONG THE ELDERLY
  • 批准号:
    7650702
  • 项目类别:
  • 资助金额:
    $38.52万
  • 财政年份:
    2009
  • 负责人:
    L. JOSEPH MELTON
  • 依托单位:
BONE DENSITY AMONG OLMSTED COUNTY RESIDENTS FROM CAMBODIA
  • 批准号:
    6264992
  • 项目类别:
  • 资助金额:
    $2.01万
  • 财政年份:
    1998
  • 负责人:
    L. JOSEPH MELTON
  • 依托单位:
BONE DENSITY AMONG AFRICAN AMERICAN RESIDENTS OF OLMSTED COUNTY
  • 批准号:
    6264994
  • 项目类别:
  • 资助金额:
    $2.01万
  • 财政年份:
    1998
  • 负责人:
    L. JOSEPH MELTON
  • 依托单位:
BONE MINERAL DENSITY MEASUREMENT IN ADULT SOMALI POPULATION
  • 批准号:
    6264965
  • 项目类别:
  • 资助金额:
    $2.01万
  • 财政年份:
    1998
  • 负责人:
    L. JOSEPH MELTON
  • 依托单位:
国内基金
海外基金
Autoimmune diseases therapies: variations on the microbiome in rheumatoid arthritis
Molecular Interaction Reconstruction of Rheumatoid Arthritis Therapies Using Clinical Data