Feasibility and Benchmarking of RiboTite gene expression control technology
Feasibility and Benchmarking of RiboTite gene expression control technology
批准号:
BB/J019089/1
负责人:
Jason Micklefield
金额:
$18.62万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2012
资助国家:
英国
项目状态:
已结题
起止时间:
2012 至 --
中文摘要
我们开发了一种新的基因表达技术,可应用于研发试剂盒市场和生物制药生产。我们计划通过目前的研究,将我们的表达技术与目前市场上可用的系统进行基准测试。这项研究将展示我们技术的技术优势的关键领域,告知其在市场上的后续定位,告知我们的业务规划,并作为私募股权投资的启动引物。这笔赠款的产出将导致与行业的合作,为BBSRC资助的研究提供影响,并可能为英国创造财富和就业机会。
英文摘要
We have developed a novel gene expression technology that has applications in the R&D kits market and in the manufacture of biopharmaceuticals. We plan through this current study to benchmark our expression technology against those systems currently available in the marketplace. This study will showcase the key areas of technical superiority of our technology, inform its subsequent positioning in the market place, inform our business planning and act as an enabling primer for private equity investment. The outputs from this grant will lead to partnering collaborations with industry, provide impact for BBSRC funded research, and potentially lead to wealth generation and job creation for the UK.
期刊论文(3)
专著(0)
科研奖励(0)
会议论文
Rewiring Riboswitches to Create New Genetic Circuits in Bacteria.
重新连接核糖开关以在细菌中创建新的遗传电路。
DOI:
10.1016/bs.mie.2016.02.022
发表时间:
2016
期刊:
Methods in enzymology
影响因子:
--
作者:
[Robinson CJ]
通讯作者:
Robinson CJ
DOI:
10.1093/nar/gkv912
发表时间:
2016-02-18
期刊:
Nucleic acids research
影响因子:
14.9
作者:
[Morra R, Shankar J, Robinson CJ, Halliwell S, Butler L, Upton M, Hay S, Micklefield J, Dixon N]
通讯作者:
Dixon N
DOI:
10.1007/978-1-62703-755-6_8
发表时间:
2014-02
期刊:
Methods in molecular biology
影响因子:
--
作者:
[H. Vincent;C. Robinson;Ming-Cheng Wu;N. Dixon;Jason Micklefield]
通讯作者:
H. Vincent;C. Robinson;Ming-Cheng Wu;N. Dixon;Jason Micklefield
Pathways to improved polyene antimicrobial agents (PIPA)
-
批准号:BB/X015645/1
-
项目类别:Research Grant
-
资助金额:$76.18万
-
财政年份:2023
-
负责人:Jason Micklefield
-
依托单位:
Engineering macrolactam antimicrobial agents (EMLA)
-
批准号:BB/X002241/1
-
项目类别:Research Grant
-
资助金额:$66.45万
-
财政年份:2023
-
负责人:Jason Micklefield
-
依托单位:
Methods for enzymatic synthesis of modified nucleic acids (MESNA)
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批准号:BB/X008991/1
-
项目类别:Research Grant
-
资助金额:$69.79万
-
财政年份:2023
-
负责人:Jason Micklefield
-
依托单位:
Enzymatic Approaches for Next Generation Peptide Synthesis
-
批准号:EP/Y023714/1
-
项目类别:Fellowship
-
资助金额:$23.84万
-
财政年份:2023
-
负责人:Jason Micklefield
-
依托单位:
Methods for bioengineering NRPS/PKS assembly lines delivering peptide natural products with electrophilic warheads.
-
批准号:BB/V016083/1
-
项目类别:Research Grant
-
资助金额:$60.0万
-
财政年份:2022
-
负责人:Jason Micklefield
-
依托单位:
Antibiotic K16: Elucidation and Engineering Pathways to New Anti-infective Agents.
-
批准号:BB/V008552/1
-
项目类别:Research Grant
-
资助金额:$62.0万
-
财政年份:2021
-
负责人:Jason Micklefield
-
依托单位:
Next Generation Enzymatic and Integrated Catalytic Approaches for Amide Synthesis
-
批准号:EP/V048929/1
-
项目类别:Research Grant
-
资助金额:$25.76万
-
财政年份:2021
-
负责人:Jason Micklefield
-
依托单位:
Exploiting Halogenase Enzymes: New Reaction Pathways via Enzymatic CH Activation
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批准号:BB/R01034X/1
-
项目类别:Research Grant
-
资助金额:$127.49万
-
财政年份:2018
-
负责人:Jason Micklefield
-
依托单位:
A Synthetic Biology Approach for the Total Biosynthesis of Semi-Synthetic Antibiotics
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批准号:BB/N023536/1
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项目类别:Research Grant
-
资助金额:$148.9万
-
财政年份:2016
-
负责人:Jason Micklefield
-
依托单位:
NATURAL PRODUCTS DISCOVERY AND BIOENGINEERING NETWORK (NPRONET)
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批准号:BB/L013754/1
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项目类别:Research Grant
-
资助金额:$198.41万
-
财政年份:2014
-
负责人:Jason Micklefield
-
依托单位:
Bioengineering of next generation lipoglycopeptide antibiotics
-
批准号:BB/L002299/1
-
项目类别:Research Grant
-
资助金额:$88.05万
-
财政年份:2013
-
负责人:Jason Micklefield
-
依托单位:
Orthogonal riboswitches as tools for controlling gene expression in bacteria
-
批准号:BB/I012648/1
-
项目类别:Research Grant
-
资助金额:$83.83万
-
财政年份:2012
-
负责人:Jason Micklefield
-
依托单位:
Directed Evolution of Enantiocomplementary Malonate Decarboxylases.
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批准号:BB/I020764/1
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项目类别:Research Grant
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资助金额:$40.5万
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财政年份:2011
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负责人:Jason Micklefield
-
依托单位:
Bioorthogonal site-selective protein immobilisation and labelling
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批准号:BB/I008055/1
-
项目类别:Research Grant
-
资助金额:$62.0万
-
财政年份:2011
-
负责人:Jason Micklefield
-
依托单位:
Manchester Chemical Biology Network
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批准号:EP/I037253/1
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项目类别:Research Grant
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资助金额:$18.9万
-
财政年份:2011
-
负责人:Jason Micklefield
-
依托单位:
Co-evolution of small molecule responsive riboswitches
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批准号:BB/D005612/1
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项目类别:Research Grant
-
资助金额:$87.73万
-
财政年份:2006
-
负责人:Jason Micklefield
-
依托单位:
国内基金
海外基金
企业绩效评价的DEA-Benchmarking方法及动态博弈研究
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批准号:70571028
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项目类别:面上项目
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资助金额:16.5万元
-
批准年份:2005
-
负责人:杨印生
-
依托单位: