ROCHESTER EPIDEMIOLOGY PROJECT

罗切斯特流行病学项目(REP)是一项独特的、以人群为基础的 数据资源由完整的(急性子和门诊)组成 所有奥姆斯特县，明尼苏达州居民的医疗记录 他们在该县的居留期限。我们的数据库现在涵盖了 几乎所有医疗服务提供者都向县城居民提供医疗服务 从1909年到现在，已经出版了565种出版物 该系统成立于1966年(自上一次比赛以来为212 五年前的续订)关于无数的主题--许多与关键 事关国家的健康问题。该代表支持一名 来自梅奥等学术机构的大批调查人员 在美国和国外，并使高效的行为成为可能 由外部资助的冠心病、中风、 痴呆症和其他神经疾病、癌症、糖尿病和其他 代谢性疾病，胃肠道疾病，骨质疏松症，关节炎， 还有其他的。尽管梅奥诊所通过索引做出了很大贡献 其本身记录的诊断、外科手术和病理 此项目免费记录，由销售代表负责 从非Mayo提供者收集诊断数据，以集成 来自所有护理来源的信息，并使所有人都能获得 有资格进行描述性和分析性研究的调查人员。续 需要支持来补充梅奥诊所的诊断指数 来自奥姆斯特德医疗集团、奥姆斯特德社区医院和 奥姆斯特德及其周围的其他几个非梅奥医疗保健来源 并承担加强研究的组织任务 罗切斯特流行病学项目的能力和提高其 效率。 申请的资金需要(1)维护并继续添加到 代表数据库的非Mayo部分，这使完整的 以人口为基础所需的病例查明和后续行动水平 在罗切斯特和奥姆斯特德县的研究，形成了 在这一人群中进行流行病学研究；(2)扩展我们的研究 通过形成新的实验室结果索引、诊断功能 程序和药物；(3)利用以下方法使数据库现代化 开发全局文件(REP)的关系数据库技术 医疗简档)包含姓名的纵向记录， 身份证号码、住处、就医经历和 住院、临床和病理诊断、外科和 诊断程序、化验值、处方药和 链接到注册在特定项目中的每个居民的详细数据 研究或登记；和(4)提高后勤保障效率 通过自动化许多样本选择、驻留的程序 验证，并用于生成和跟踪后续通信， 并通过建立与国家死亡指数的接口。

The Rochester Epidemiology Project (REP) is a unique, population-based data resource comprised of the complete (impatient and outpatient) medical records of all Olmsted County, MN residents for the entire duration of their residency in the County. Our data base now covers the medical care delivered by essentially all providers to County residents from 1909 through the present and has resulted in 565 publications since the system was organized in 1966 (and 212 since the last competitive renewal five years ago) on a myriad of topics--many relating to critical health issues of national importance. The REP supports the work of a large number of investigators from Mayo and other academic institutions in the United States and abroad and makes possible the efficient conduct of extramurally funded studies of coronary heart disease, stroke, dementia and other neurological conditions, cancer, diabetes and other metabolic diseases, gastrointestinal disorders, osteoporosis, arthritis, and other. Although Mayo Clinic contributes substantially by indexing the diagnoses, surgical procedures and pathology recorded in its own records at no cost to this project, it is the responsibility of the REP to collect the diagnostic data from non-Mayo providers, to integrate the information from all sources of care, and to make it accessible to all qualified investigators for descriptive and analytic studies. Continued support is needed to supplement the Mayo Clinic diagnostic index with data from the Olmsted Medical Group, the Olmsted Community Hospital and several other non-Mayo sources of medical care in and around Olmsted County and to undertake organizational tasks that enhance the research capabilities of the Rochester Epidemiology Project and increase its efficiency. The funds requested are required to (1) maintain and continue adding to the non-Mayo portion of the REP data base, which makes possible the full level of case ascertainment and follow-up required for population-based studies in Rochester and Olmsted County and forms the essential core for epidemiologic research in this population; (2) extend our research capabilities by forming new indexes for laboratory results, diagnostic procedures and medications; (3) modernize the data base by using relational data base technology to develop a global file (the REP Medical Profile) containing a longitudinal record of names, identification numbers, residences, episodes of medical care and hospitalization, clinical and pathological diagnoses, surgical and diagnostic procedures, laboratory values, prescription drugs, and linkages to the detailed data of each resident enrolled in a specific study or registry; and (4) enhance the efficiency of logistical support by automating many of the procedures for sample selection, for residency verification, and for generating and tracking follow-up correspondence, and by establishing an interface with the National Death Index.