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Delivering ELIXIR-UK

Delivering ELIXIR-UK
交付 ELIXIR-UK
批准号:
BB/L005069/1
负责人:
Chris Ponting
金额:
$131.42万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2014
资助国家:
英国
项目状态:
已结题
起止时间:
2014 至 --
关键词:

项目摘要

项目成果

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中文摘要
翻译
ELIXIR是一个旨在为欧洲生物信息建设和运营可持续基础设施的项目。由于缺乏能够利用大型生物数据集的个人,我们决定将英国的ELIXIR节点集中在培训上。这是一个生物学的世纪,基因组学、转录组学、蛋白质组学和代谢组学(组学和生物信息学)是这个世纪的核心。计算机是一个必不可少的工具,现在驱动着科学过程的许多关键方面,因此科学家需要知道如何从它中获得最大的优势。尽管计算在今天的科学中发挥着核心作用:-大多数研究科学家没有能力利用新技术带来的数据“富矿”。整个社区的关键培训需求在分析和解释多种类型的基因组规模数据方面,包括下一代测序(NGS)数据。基因组学是最需要培训的领域,因为它位于许多快速发展的研究学科的交叉点。-许多基础设施技术专家(职业生物信息学家)没有能力提供可扩展的、可持续的解决方案来管理和解释这一技术进步浪潮所产生的数据。关键的培训需求是数据管理、集成、计算和软件、工具、服务和标准方面的技术和实践。ELIXIR-UK的核心机构是:牛津大学、曼彻斯特大学、利物浦大学、伯明翰大学和爱丁堡大学;环境组学综合中心;威康信托基金会桑格研究所;基因组分析中心;伦敦大学学院。其他参与组织包括:英国软件可持续发展研究所;哈特里中心;以及邓迪大学。其他组织(英国和elixir范围内)将被纳入提供培训。
英文摘要
ELIXIR is a project that is designed to construct and operate a sustainable infrastructure for biological information in Europe. Owing to the dearth of individuals who can take advantage of large biological data sets, we have decided to focus the UK's ELIXIR node on training.This is the century of biology, and genomics, transcriptomics, proteomics and metabolomics ('omics and bioinformatics) lie at its heart. The computer is an essential tool and now drives many critical aspects of the scientific process hence scientists need to know how to gain most advantage from it. Despite the central role of computing in science today:- Most research scientists are ill-equipped to take advantage of the data 'bonanza' that is emanating from new technologies. Critical training needs across the community are, broadly, in the analysis and the interpretation of genome-scale data of many types, including next generation sequencing (NGS) data. Genomics is the area of greatest training need as it lies at the intersection of many fast-moving research disciplines.- Many infrastructure technologists (career bioinformaticians) are ill-equipped to offer scalable, sustainable solutions for managing and interpreting data arising from this flood of technological advances. Critical training needs are in techniques and practices for data management, integration, compute and software, tools, services and standards.The ELIXIR-UK Core Organisations are: the Universities of Oxford, Manchester, Liverpool, Birmingham, and Edinburgh; the NERC Environmental Omics Synthesis Centre; the Wellcome Trust Sanger Institute; the Genome Analysis Centre; and, University College London. Additional participating organisations are: the Software Sustainability Institute UK; the Hartree Centre; and the University of Dundee. Other organisations (UK and ELIXIR-wide) will be incorporated to provision training.
期刊论文(9)
专著(0)
科研奖励(0)
会议论文
Data discovery with DATS: exemplar adoptions and lessons learned.
数据发现数据:示例采用和经验教训。
DOI: 10.1093/jamia/ocx119
发表时间: 2018-01-01
期刊: Journal of the American Medical Informatics Association : JAMIA
影响因子: --
作者: [Gonzalez-Beltran AN, Campbell J, Dunn P, Guijarro D, Ionescu S, Kim H, Lyle J, Wiser J, Sansone SA, Rocca-Serra P]
通讯作者: Rocca-Serra P
DOI: 10.12688/wellcomeopenres.16378.2
发表时间: 2020
期刊: Wellcome open research
影响因子: --
作者: [Austin CC, Bernier A, Bezuidenhout L, Bicarregui J, Biro T, Cambon-Thomsen A, Carroll SR, Cournia Z, Dabrowski PW, Diallo G, Duflot T, Garcia L, Gesing S, Gonzalez-Beltran A, Gururaj A, Harrower N, Lin D, Medeiros C, Méndez E, Meyers N, Mietchen D, Nagrani R, Nilsonne G, Parker S, Pickering B, Pienta A, Polydoratou P, Psomopoulos F, Rennes S, Rowe R, Sansone SA, Shanahan H, Sitz L, Stocks J, Tovani-Palone MR, Uhlmansiek M, Research Data Alliance]
通讯作者: Research Data Alliance
DOI: 10.1093/jamia/ocx121
发表时间: 2018-03-01
期刊: Journal of the American Medical Informatics Association : JAMIA
影响因子: --
作者: [Chen X, Gururaj AE, Ozyurt B, Liu R, Soysal E, Cohen T, Tiryaki F, Li Y, Zong N, Jiang M, Rogith D, Salimi M, Kim HE, Rocca-Serra P, Gonzalez-Beltran A, Farcas C, Johnson T, Margolis R, Alter G, Sansone SA, Fore IM, Ohno-Machado L, Grethe JS, Xu H]
通讯作者: Xu H
Computational and Disease Genomics
  • 批准号:
    MC_UU_00035/14
  • 项目类别:
    Intramural
  • 资助金额:
    $14.27万
  • 财政年份:
    2023
  • 负责人:
    Chris Ponting
  • 依托单位:
A genome-wide association study of myalgic encephalomyelitis / chronic fatigue syndrome(ME/CFS)
  • 批准号:
    MC_PC_20005
  • 项目类别:
    Intramural
  • 资助金额:
    $416.75万
  • 财政年份:
    2020
  • 负责人:
    Chris Ponting
  • 依托单位:
Computational and Disease Genomics
  • 批准号:
    MC_UU_00007/15
  • 项目类别:
    Intramural
  • 资助金额:
    $325.05万
  • 财政年份:
    2018
  • 负责人:
    Chris Ponting
  • 依托单位:
Delivering ELIXIR-UK
  • 批准号:
    BB/L005069/2
  • 项目类别:
    Research Grant
  • 资助金额:
    $69.78万
  • 财政年份:
    2016
  • 负责人:
    Chris Ponting
  • 依托单位:
海外基金