SUBVISUAL DIAGNOSTIC CLUES IN CANCER DIAGNOSIS

源自的潜视标记功能的诊断实用程序 显微分光光度测量在组织病理学和临床应用中的应用 甲状腺肿瘤患者的细胞病理标本 伴有宫颈癌前病变和恶性病变的人将 下定决心。标志特征在视觉正常中的表达 细针抽吸物中可见腺核 甲状腺将会被量化。城市的空间延伸 标记特征在组织学正常外观中的表达 组织学切片上病变周围的组织 甲状腺和宫颈外膜将会被确定。 早期对发育不良患者表达的标记特征的研究 宫颈外细胞将继续和延伸，将 组织切片中细胞核的测量。他们的预测 预测先兆病变生物学行为的可能性 还将探讨宫颈癌的发病机制。 将进行探索性研究以寻找标记 组织学形态正常的粘膜中的特征表达 邻近的结直肠肿瘤区域。 我们廉价的分析能力 视频显微光度计将升级为提取相关的 特征，包括核质地措施。

The diagnostic utility of subvisual marker features derived from microphotometric measurements in histopathological and cytopathological samples for patients with thyroid tumor patients with premalignant and malignant lesions of the cervix will be determined. The expression of marker features in visually normal appearing glandular nuclei from fine needle aspirates of the thyroid will be quantitated. The spatial extension of the expression of marker features into histologically normal appearing tissues surrounding the lesion in histological sections of the thyroid and ectocervix will be determine. Earlier work on the marker features expressed in dysplastic ectocervical cells will be continued and extended, will measurements on nuclei in histologic sections. Their prognostic potential in predicting the biological behavior of precursor lesion of cervical cancer will be explored. An exploratory study will be conducted to search for marker feature expression in histologically normal appearing mucosa adjoining colorectal tumor regions. The analytic capabilities of our inexpensive videomicrophotometer will be upgraded to extract pertinent features, including nuclear texture measures.