National Live Cell Scanning Platform for Nanoparticle Tracking

国家活细胞纳米颗粒跟踪扫描平台：该项目的目标是建立一个多学科、多用户、自相关的扫描设备，以达到实时跟踪和定量大量活细胞内生物分子和纳米颗粒的时间和空间精度的新水平。该设施将包括一个活细胞旋转盘共聚焦显微镜，一个相关的生物原子力显微镜和远程访问设施。预计凭借优越的光学特性和机械操作，自动化正交扫描设备将开辟新的途径，揭示前所未有的生物和病理过程信息。该合作设施将支持物理、材料和生命科学等多学科领域的世界级研究人员，将澳大利亚置于纳米级生物光子学的前沿。

National live cell scanning platform for nanoparticle tracking: The aim of the project is to establish a multi-disciplinary, multi-user, self-correlated scanning facility to reach a new level of temporal and spatial precision for real-time tracking and quantification of biomolecules and nanoparticles within large populations of living cells. The facility will consist of a live-cell spinning-disc confocal microscope, a correlated biological atomic force microscope, and remote access facilities. It is expected that with superior optical characterisation and mechanical manipulation, the automated orthogonal scanning facility will open new avenues to reveal unprecedented information from biological and pathological processes. The collaborative facility will support world-class researchers in the multi-disciplinary areas of physical, material and life sciences, placing Australia at the forefront of nanoscale biophotonics.