Development of a Nucleoside Diphosphate Platform for the Chemo-Enzymatic Synthesis of Nucleoside Triphosphates

三磷酸核苷（NTPs）是储存遗传物质的核酸组装的自然原料。我们已经开发了一种基于酶的方法，使我们能够制备ntp。我们在我们的过程中使用廉价的材料，然而，我们不确定我们的系统是多么有效或广泛适用，或者它与其他已知的酶系统相比如何。我们收集了独立的市场研究，表明我们的系统可能对实业家有广泛的兴趣。然而，通过这次协商，很明显，在工业界考虑采用我们的制度之前，需要进一步了解其范围的广度和局限性。此外，我们还需要将我们的系统从研究实验室的东西转变为可以在化工厂中稳定使用的东西。提出的工作旨在拓宽我们的理解，并将我们的研究转化为工业应用

Nucleoside triphosphates (NTPs) are Nature's raw materials for the assembly of the nucleic acids that store genetic material. We have developed an enzyme-based method that allows us to prepare NTPs. We use inexpensive materials in our processes, however, we are not sure how efficient or broadly-applicable our system is or how it compares to other known enzyme systems. We have gathered independent market research to show that our system could have broad interest to industrialists. Through this consultation, however, it was clear that further information on the breadth of scope and the limitations of our system were required before industry could consider adopting it. Furthermore, we also need to convert our system from something that works in a research laboratory into something that can be employed robustly on a chemical plant. The proposed work aims to broaden our understanding and translate our research towards industrial applications