THE EPIDEMIOLOGY OF PERSISTENT CHILD PSYCHOPATHOLOGY

这项建议中描述的流行病学研究是基于近 对随机抽样的1至10岁孩子的母亲进行了1000次采访。 关于孩子们的情绪和行为 问题和能力、儿童健康史、儿童养育和 原始浪潮中的其他家庭结构和环境变量 1975年期间的数据收集。对这些人进行心理测量和实质性研究 数据将在本赠款期间完成。 对母亲和儿童的后续采访已经进行 当孩子们9到18岁的时候。重访包括DSM III 基于诊断性面谈，从原始面谈中得出的量表， 以及关于家庭和家庭外环境的广泛数据。此外, 对100个家庭的重新采访将提供临床验证 已完成，为评估和改进 进行诊断性访谈。 当前提案的具体目标包括心理测量学。 研究诊断中的方法学问题。改进了 然后，基于这些分析的诊断仪器将应用于 新一波数据收集，其中母亲和儿童将再次 使用旨在涵盖相同问题的结构化工具进行采访 在当前一波中得到了解决。此外，对一个样本的重新采访 年龄较大的孩子，现在15岁到20岁，将与成年人一起携带 不是的。这一子研究将使诊断能够转化为 该样品的仪器和与其他现有样品的比较。 这些数据将被用来确定艾滋病的流行率和持久性 儿童的精神障碍及其在儿童精神障碍问题中的先兆 童年早期。在所有三个时间点收集的数据将是 被用来确定精神病的危险因素和伴随因素。在……里面 此外，这项研究将评估这些风险因素的一般性，并 他们对生活在不同家庭外的儿童的相对潜力 环境。数据分析将包括复制以前的 发现表明不同的环境影响，并测试 理论上和经验上的，以及派生的模型。

The epidemiological study described in this proposal is based on nearly 1000 interviews of mothers of randomly sampled children ages 1 to 10. Data were collected with regard to the children's emotional and behavioral problems and competencies, children's health histories, child rearing and other family structure and environmental variables in the original wave of data collection during 1975. Psychometric and substantive studies of these data will have been completed during the current grant period. Follow up interviews of both mothers and children have been carried out when the children were ages 9 to 18. The reinterviews included DSM III based diagnostic interviews, scales derived from the original interviews, and extensive data on familial and extrafamilial environment. In addition, a reinterview of 100 families to provide a clinical validation will have been completed to provide the basis for assessment and improvement of the lay diagnostic interviews. The specific aims for the current proposal include psychometric investigations into methodological issues in diagnosis. Improvements in the diagnostic instrument based on these analyses will then be applied in a new wave of data collection in which mothers and children will again be interviewed with a structured instrument designed to cover the same issues addressed in the current wave. In addition, a reinterview of a sample of the older children, now ages 15 to 20, will be carried out with the adult DIS. This substudy will enable a translation of diagnosis across instruments and comparison of this sample with other available samples. The data will be employed to determine the prevalence and persistance of psychiatric disorders in children and their antecedents in the problems of early childhood. Data collected at all three points in time will be employed to determine risk factors and concomitants of psychopathology. In addition, the study will assess the generality of these risk factors and their relative potencies for children living in different extra-familial environments. The data analysis will include replication of previous findings suggesting differential environmental effects, and testing of theoretically and empirically and derived models.