Neurobiology of parenting and disruptive behaviour disorders in childhood

该项目旨在研究遗传决定因素和父母对儿童破坏性行为障碍的贡献。这些疾病往往是慢性的，并与晚年的共病状况有关，给个人和家庭带来巨大的个人和社会成本，并给经济带来负担。大约三分之一的儿童对目前形式的早期干预没有反应，因此临床医生需要父母的做法和这些疾病的发展方面之间的相互作用的证据。该项目将研究具有破坏性行为障碍的幼儿及其父母的催产素遗传学，最终确定形成持续性障碍的遗传，家庭和发展过程。

This project aims to examine the genetic determinants and contribution of parenting to childhood disruptive behaviour disorders. These disorders are often chronic and associated with comorbid conditions in later life, creating enormous personal and social costs for individuals and families, and a burden on the economy. About a third of children do not respond to current forms of early intervention, so clinicians need evidence of the interaction between parenting practices and the developmental aspects of these disorders This project will examine oxytocin genetics in toddlers with disruptive behaviour disorders and their parents, to ultimately identify the genetic, family, and developmental processes that shape persistent disorders.