MODULATION OF MEMORY

长期目标是增加对基本知识的了解 信息存储和检索中的心理生物学过程。这个 确定、评估和描述各种目标的具体目标 记忆的转换涉及四个主要研究领域： 1)控制顺行性遗忘症的变量分析 人类常见的记忆病理类型。无论发烧状态和 其他常见的动态平衡紊乱可以作为顺行的来源。 记忆力丧失也将被确定。2)检视 在获取和测试期间的独特上下文在缓解 个体发育性遗忘(婴儿健忘症)。这些研究将调查 缓解效果的必要条件，并探索 其他来源的记忆损失可以通过这种类型减少的可能性 被操控。3)旧信息调制问题的研究 它已被重新激活(检索)。的变化的性质 由记忆治疗反条件作用产生的享乐值将是 检查过了。这一主题不仅对理解延展性很重要 但也是为了潜在地澄清可能 是脱敏等临床治疗的基础。4)评估 忘记刺激属性，这是记忆中相对被忽视的一个方面 现象。此外，这项工作还将评估 忘记刺激特征允许更多的干扰和 从而损害了对目标反应的检索。

The long term objective is to increase knowledge about basic psychobiological processes in storage and retrieval of information. The specific aims of identifying, assessing, and delineating various transformations of memory are addressed in four major areas of research: 1) Analysis of variables controlling anterograde amnesia, which is a frequent type of memory pathology in humans. Whether fever states and other common disruptions of homeostasis can act as sources of anterograde memory loss also will be determined. 2) Examination of the role of distinctive contexts during acquisition and testing in alleviating ontogenetic forgetting (infantile amnesia). These studies will investigate the necessary conditions for the alleviation effect, and explore the possibility that memory loss from other sources can be reduced by this type of manipulation. 3) Investigation of the modulation of old information which has been reactivated (retrieved). The nature of the change in hedonic value produced by a counterconditioning of memory treatment will be examined. This topic is important not only for understandng malleability of memory but also for potentially clarifying processes which presumably underlie clinical therapies such as desensitization. 4) Assessment of forgetting of stimulus attributes, a relatively neglected aspect of memory phenomena. In addition, this work will evaluate the implication that forgetting of stimulus characteristics permits increased interference and thus impaired retrieval of the target response.