Sequence-defined polymers and green chemistry

该项目旨在合成具有精确化学结构的聚合物，并模仿天然生物聚合物（如多肽和蛋白质）的生物活性。这些天然生物聚合物的单体序列调控在生物学中是重要的，对于分子识别、自我复制和催化等生命的关键特征是必要的。目前合成生物聚合物的人工技术耗时长，成本高，产率低。该项目预计其新材料将提高制造业的可持续性、化学多样性和工业可行性；通过改进化疗和疾病诊断，为澳大利亚的健康带来益处；并使澳大利亚经济受益。

This project aims to synthesise polymers that have precise chemical structure and mimic the biological activities of natural biopolymers like peptides and proteins. Monomer sequence regulation in these natural biopolymers is important in biology and necessary for crucial features of life, such as molecular recognition, self-replication and catalysis. Current artificial techniques for biopolymer synthesis are time consuming and present low yields at high costs. This project expects its new materials will increase manufacturing sustainability, chemical diversity and industrial viability; produce health benefits for Australia by improving chemotherapy and diagnosis for diseases; and benefit the Australian economy.