A cellular identity crisis: Deciphering how mammary epithelial cells form and maintain their identity

能够从成年细胞中高效、无差错地再生人体器官是澳大利亚生物医学研究的主要目标，具有显著的经济效益。作为女性体内最具再生能力的器官之一，乳房是研究组织生长和再生机制的极佳模型。此外，由于这些通路经常被癌症劫持，这项研究对开发治疗乳腺癌的新靶向疗法具有重要意义。

The ability to regenerate human organs from adult cells efficiently and without error is a major goal of biomedical research in Australia, with significant economic benefits. As one of the most regenerative organs in a woman's body, the breast is an excellent model to study mechanisms that underpin tissue growth and regrowth. Moreover, as these pathways are often hijacked by cancer, this research has important implications for the development of new targeted therapies to treat breast cancer.