EFFICACY OF COCAINE TREATMENTS--A COLLABORATIVE STUDY

可卡因滥用在美国已经达到流行的程度 各州。尽管问题很严重，但人们对此知之甚少。 治疗的有效性。此应用程序建议 确定两种流行形式的比较疗效 依赖者的住院和门诊治疗 并确定相对成本效益(CE) 以及这两种处理的成本效益(CB)。其他目标是 测试有关治疗结果的假设 社会学习和社会支持理论，并汇编 被研究样本的描述性数据。样品将会 由劳动大军中的人(蓝领到 专业人士)在私人非营利性组织寻求治疗 扇区。研究设计，回归不连续，是一种 强大的准实验替代随机化 分配给治疗人员。使用这种设计，患有严重疾病的受试者 可卡因依赖和相关的心理社会问题 分配给住院治疗和病情较轻的受试者 家属将被分配到门诊治疗。科目 将在治疗开始时、治疗中和12个月内进行评估 在退出治疗几个月后。两大类 将评估结果：药物使用，包括可卡因的使用， 酒精和其他毒品；以及心理社会功能，包括 在就业、家庭和其他社会领域发挥作用 关系，以及医疗保健。大约600名男性和女性 在整个加利福尼亚州，从21岁到58岁，谁 参加可卡因的住院或门诊治疗 依赖性将被纳入这项研究。这项研究将是 在CALNET的成员计划中进行，CALNET是一个广泛的网络 以医院为基础的药物依赖康复服务 为超过50%的县的居民提供护理 加利福尼亚。以便全面评估 待研究的治疗方法，这项研究将适用于经济 CE和CB方法对可卡因依赖的治疗。 这些经济评估分析将提供关键的 政策和治疗决策的信息。

Cocaine abuse has reached epidemic proportions in the United States. Despite the scale of the problem, little is known about effectiveness of treatments. This application proposes to determine the comparative efficacy of two prevalent forms of treatment, inpatient and outpatient, for persons with dependence on cocaine and also to determine relative cost-effectiveness (CE) and cost-benefits (CB) of these two treatments. Other goals are to test hypotheses regarding treatment outcomes derived from social learning and social support theories and to compile descriptive data of the sample under study. The sample will consist of persons who are in the work force (blue-collar to professionals) who seek treatment in the private non-profit sector. The research design , regression discontinuity, is a powerful quasi-experimental alternative to randomized assignment to treatments. Using this design, subjects with severe cocaine dependency and related psychosocial problems will be assigned to inpatient treatment and subjects with less severe dependency will be assigned to outpatient treatment. Subjects will be assessed at treatment entry, in-treatment, and for 12 months following exit from treatment. Two major categories of outcome will be assessed: drug use, including use of cocaine, alcohol and other drugs; and psychosocial functioning, including functioning in the areas of employment, family and other social relations, and health care. Approximately 600 men and women throughout the state of California, from 21-58 years of age, who enroll in inpatient or outpatient treatment for cocaine dependency will be recruited into the study. The study will be conducted at member programs of CALNET, an extensive network of hospital-based chemical dependency recovery services that provides care to residents of over 50% of the counties in California. To allow for comprehensive evaluation of the treatments to be studied, this research will apply economic CE and CB methods to the treatment of cocaine dependency. These economic appraisal analyses will provide critical information for policy and treatment decisions.