Chromatin Dynamics as a Driver of Disease Initiation and Development
Chromatin Dynamics as a Driver of Disease Initiation and Development
批准号:
nhmrc : GNT1109696
负责人:
Dr Phillippa Taberlay
金额:
$41.92万
依托单位国家:
澳大利亚
项目类别:
Career Development Fellowships
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 --
中文摘要
表观遗传编程确保了正确的基因在正确的时间以正确的数量在正确的细胞类型中表达。我们的总体目标是确定在某些癌症和痴呆症中这种编程是如何改变的,并确定这是否是疾病的原因或驱动因素。这项研究具有确定表观遗传标记的巨大潜力,这些标记将成为新疗法的最佳靶点。
英文摘要
Epigenetic programming ensures that the right genes are expressed in the right amount, in the right cell type at the right time. Our OVERALL AIM is to identify how this programming is altered in certain cancers and dementias and to determine whether this is a cause or driver of disease. This study has great potential to identify the epigenetic marks that will be the best targets for new therapies.
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Chromatin Dynamics as a Driver of Disease Initiation and Development
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批准号:nhmrc : 1109696
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项目类别:Career Development Fellowships
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资助金额:$30.5万
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财政年份:2016
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负责人:Dr Phillippa Taberlay
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依托单位:
BEYOND TRADITIONAL GENE BOUNDARIES: Establishing the importance of enhancer epigenetic reprogramming and atypical long-range interactions in cancer cells.
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批准号:nhmrc : 1051757
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项目类别:Project Grants
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资助金额:$47.91万
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财政年份:2013
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负责人:Dr Phillippa Taberlay
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依托单位:
国内基金
海外基金
β-arrestin2- MFN2-Mitochondrial Dynamics轴调控星形胶质细胞功能对抑郁症进程的影响及机制研究
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批准号:
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项目类别:省市级项目
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资助金额:--
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批准年份:2023
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负责人:
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依托单位: