RESEARCH IN CANCER EPIDEMIOLOGY AND BIOSTATISTICS

我这个项目的目标是开发和使用生物统计学， 旨在减少癌症的生物数学和流行病学方法 发生了。我的研究目标有两个。首先，我 将开发进行流行病学研究的新方法 癌症病因学与个人特征的关系， 生活方式元素和环境暴露。具体来说，我 将开发更好的方法来设计和分析研究 曝光错误，更好地分析来自 多中心研究，以及寻找不寻常模式的更好方法 在基于人群的癌症发病率数据中。第二，我将使用 这些方法用于收集和分析与特定站点相关的数据 癌症的发生与可改变的生活方式因素和 暴露在环境中。用于分析的现有数据包括 来自一项对大学男性特定部位癌症的前瞻性研究 而女性，来自卵巢癌病例对照研究的数据， 乳房和大肠，以及监控中心的数据， 流行病学和最终结果(SEER)与加州肿瘤 注册处。新数据将从最近资助的 非霍奇金淋巴瘤的五年研究和未来 前列腺癌和卵巢癌的多中心研究。

My goals for this project are to develop and use biostatistical, biomathematical and epidemiologic methods aimed at reducing cancer occurrence. The objectives of my research are twofold. First, I will develop new methods for the conduct of epidemiologic studies of cancer etiology in relation to personal characteristics, lifestyle elements and environmental exposures. Specifically, I will develop better ways to design and analyze studies with exposure errors, better ways to analyze combined data from multicenter studies, and better ways to search out unusual patterns in population-based cancer incidence data. Second, I will use these methods to collect and analyze data relating site-specific cancer occurrence to modifiable lifestyle elements and environmental exposures. Existing data for analyses include data from a prospective study of site-specific cancers in college men and women, data from case-control studies of cancers of the ovary, breast, and large bowel, and data from the Surveillance, Epidemiology and End Results (SEER) and California tumor registries. New data will be generated from a recently funded five-year study of nonHodgkin's lymphoma, and from future multicenter studies of cancers of the prostate and ovary.