EPSRC-NIHR HTC Partnership Award 'Plus': NewMind - Partnership with the MindTech HTC.

这是一项扩展工程和物理科学（EPS）研究人员之间现有伙伴关系的提案，这些研究人员来自一系列大学和NIHR MindTech医疗保健技术合作组织。其目的是探索技术的潜力，以改变精神健康状况的管理和治疗，确定基础EPS研究挑战，并共同努力解决这些问题。心理健康已占国民保健服务预算的13%（在所有疾病领域中所占比例最高，而且还在迅速增长），是生活质量下降的一个主要原因。大多数护理是在社区进行的，但大部分费用与由于护理不足或无效而导致的计划外住院有关。技术在改变社区护理方面有着巨大的潜力——改进诊断、实现分层（识别不同的子群体）、支持自我护理、更有效地让家人和朋友参与进来，以及为医疗保健专业人员提供及时的提示和警报。然而，如果要实现这一潜力，就需要解决重大的EPS挑战。我们建立了一个多学科网络（NewMind），包括工程和物理科学研究人员、医疗保健专业人员、心理健康服务用户、心理健康慈善机构的代表和行业，在过去的18个月里，该网络的成员稳步增长，达到220人。我们还制定了健康成果框架和工程与物理科学研究路线图，为未来的研究提供信息。我们现在寻求延长网络的寿命，并获得资金来支持探索性和可行性项目。NewMind网络专注于具有重大社会重要性的四个广泛临床领域，与NIHR MindTech HTC议程保持一致：严重精神疾病，情绪和情感障碍，痴呆和发育障碍-每个领域都有临床领导-利用诺丁汉（NIHR MindTech HTC）和曼彻斯特的精神卫生专业知识。我们目前确定了四个具有挑战性的EPS研究领域，这些领域需要支持有效技术的发展，以管理心理健康状况的自我护理：用于获取丰富的“实时”纵向数据的传感系统；集成和链接异构信息和数据的信息管理方法；用于提取预测模型的数据分析，特别是从时间数据中提取预测模型；和以人为中心的系统方法管理自我保健设置，提供协作决策支持。

This is a proposal to extend an existing partnership between engineering and physical science (EPS) researchers from a range of universities and the NIHR MindTech Healthcare Technology Cooperative. The aim is to explore the potential for technology to transform the management and treatment of mental health conditions, identifying underpinning EPS research challenges, and working together to address them. Mental health already accounts for 13% of the NHS budget (the highest proportion for any disease area, and growing rapidly) and is a major cause of reduced quality of life. Most care is in the community, but most of the cost is associated with unplanned hospital admissions resulting from inadequate or ineffective care. There is great potential for technology to transform care in the community - improving diagnosis, enabling stratification (identifying different sub-groups), supporting self-care, involving family and friends more effectively, and providing timely prompts and alerts for healthcare professionals. If this potential is to be realised, there are, however, significant EPS challenges to be addressed. We have established a multidisciplinary network (NewMind), involving engineering and physical science researchers, healthcare professionals, users of mental health services, representatives of mental health charities, and industry, which has grown steadily over the past 18 months to a membership of 220. We have also developed a Health Outcomes Framework and Engineering and Physical Science Research Roadmap, to inform future research. We now seek to extend the lifetime of the network, and obtain funding to support exploratory and feasibility projects.The NewMind network focuses on four broad clinical areas of major societal importance, aligned with the NIHR MindTech HTC agenda: serious mental illness, mood and affective disorder, dementia, and developmental disorders - each with clinical leadership - drawing on mental health expertise in both Nottingham (the NIHR MindTech HTC) and Manchester.We currently identify four areas of challenging EPS research required to underpin the development of effective technologies for managed self-care of mental health conditions: sensing systems for acquiring rich, 'real-time' longitudinal data; information management methods for integrating and linking heterogeneous information and data; data analytics for extracting predictive models, particularly from temporal data; and human-centric systems methods for themanaged self-care setting, providing collaborative decision-support.