EPSRC-NIHR HTC Partnership Award 'Plus': UNIFY Plus
EPSRC-NIHR HTC Partnership Award 'Plus': UNIFY Plus
批准号:
EP/N027221/1
负责人:
David John Williams
金额:
$46.42万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2016
资助国家:
英国
项目状态:
已结题
起止时间:
2016 至 --
中文摘要
该提案的重点是解决骨不连骨折修复和康复中未满足的主要临床需求。骨不连是一种无法愈合的骨折。这些都是平民和军人受伤造成的,导致痛苦、苦难和丧失尊严。与创伤健康技术合作组织合作的最初的BAURY网络已经确定,需要对骨形成有更基本的了解,以解决骨不连和其他密切相关的疾病状态。“可持续发展年+”以可持续发展年为基础,以便更好地安排实地工作,并对解决这些问题的有希望的办法进行可行性研究。
英文摘要
This proposal is focussed on addressing major unmet clinical needs in the repair and rehabilitation of non-union fractures. A non-union is a broken bone that fails to heal. These result from both civilian and military injuries and lead to pain, suffering and loss of dignity. The initial UNIFY network working with the Trauma Health Technology Cooperative has identified that more fundamental understanding is required of bone formation to address non-union and other closely related disease states. UNIFY Plus builds on UNIFY to permit work to better structure the field and feasibility studies of promising approaches to address the issues.
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DOI:
10.1186/s12915-020-00884-3
发表时间:
2020-10-20
期刊:
BMC biology
影响因子:
5.4
作者:
[Fleming JW, Capel AJ, Rimington RP, Wheeler P, Leonard AN, Bishop NC, Davies OG, Lewis MP]
通讯作者:
Lewis MP
DOI:
10.3389/fphys.2018.00483
发表时间:
2018
期刊:
Frontiers in physiology
影响因子:
4
作者:
[Jones JM, Player DJ, Martin NRW, Capel AJ, Lewis MP, Mudera V]
通讯作者:
Mudera V
Preclinical therapies to prevent or treat fracture non-union: A systematic review.
预防或治疗裂缝非工会的临床前疗法:系统评价。
DOI:
10.1371/journal.pone.0201077
发表时间:
2018
期刊:
PloS one
影响因子:
3.7
作者:
[Bennett PM, Stewart SK, Dretzke J, Bem D, Penn-Barwell JG]
通讯作者:
Penn-Barwell JG
DOI:
10.1007/s10974-020-09589-0
发表时间:
2021-06
期刊:
Journal of muscle research and cell motility
影响因子:
2.7
作者:
[Aguilar-Agon KW, Capel AJ, Fleming JW, Player DJ, Martin NRW, Lewis MP]
通讯作者:
Lewis MP
EPSRC - NIHR Healthcare Technology Co-operative (HTC) Partnership Award - Unify: A network focused on the treatment of fracture non-unions
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批准号:EP/M000230/1
-
项目类别:Research Grant
-
资助金额:$19.07万
-
财政年份:2014
-
负责人:David John Williams
-
依托单位:
E-TERM, Engineering Tissue Engineering and Regenerative Medicine
-
批准号:EP/I017801/1
-
项目类别:Research Grant
-
资助金额:$367.57万
-
财政年份:2012
-
负责人:David John Williams
-
依托单位:
LSI DTCs 2007-Doctoral Training Centre for Regenerative Medicine
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批准号:EP/F500491/1
-
项目类别:Training Grant
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资助金额:$911.76万
-
财政年份:2008
-
负责人:David John Williams
-
依托单位:
A Preservation and Packaging Platform for Cell and Tissue Based Therapies
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批准号:TS/G000263/1
-
项目类别:Research Grant
-
资助金额:$23.95万
-
财政年份:2008
-
负责人:David John Williams
-
依托单位:
Bridging the physical and life sciences-cementing the alliance of Loughborough University and the UHL NHS Trust
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批准号:G0502250/1
-
项目类别:Research Grant
-
资助金额:$44.64万
-
财政年份:2006
-
负责人:David John Williams
-
依托单位:
海外基金