NOVEL SOFT X-RAY IMAGING MICROSCOPE DIFFRACTION PLATE
NOVEL SOFT X-RAY IMAGING MICROSCOPE DIFFRACTION PLATE
批准号:
3498596
负责人:
JOSEPH BLANC
金额:
$5.0万
依托单位国家:
美国
项目类别:
财政年份:
1991
资助国家:
美国
项目状态:
已结题
起止时间:
1991-09-01 至 1992-03-31
中文摘要
X射线光学中的一个新想法可以提高通过成像软件的通量
X射线显微镜的一个数量级。 如此显著的进步
在开发小规模商业X-
射线显微镜,用于实验室现有设备。
该装置是一种软X射线衍射板,也可以消除昂贵的,
难以制造聚光器光学器件并减少对准限制。
详细的数学模型的衍射板将开发
使用分析和计算机技术。 这些将被用来决定
几种制造方法中哪一种能产生最好的衍射
通过比较18.2 nm激光器获得的数据,
普林斯顿等离子体物理实验室的理论。
在这些试验的基础上,将研制出一种软X射线成像显微镜。
设计包含衍射板,准备在
第二阶段。 这种仪器将使成像方面的工作大有希望
水合生物标本在50纳米分辨率目前正在做的,
将同步加速器转移到大学实验室环境中-
它有望对微观结构产生重要的见解,
含水的未染色的细胞
英文摘要
A new idea in x-ray optics could improve the flux through an imaging soft
x-ray microscope by an order of magnitude. Such a significant improvement
would be particularly important in developing a small scale, Commercial x-
ray microscope for use in laboratories alongside existing equipment.
The device, a soft x-ray diffraction plate, would also eliminate costly,
difficult to fabricate condenser optics and reduce alignment constraints.
Detailed mathematical models of the diffraction plate will be developed
using analytical and computer techniques. These will be used to decide
which of several methods of manufacture will produce the best diffraction
plates by comparing the data obtained with the 18.2 nm lasers at
Princeton's Plasma Physical Laboratory with theory.
On the basis of these tests, a soft x-ray imaging microscope will be
designed incorporating a diffraction plate, ready for construction in
Phase II. Such an instrument would enable promising work on imaging
hydrated biological specimens at 50 nm resolution currently being done at
synchrotrons to be transferred to the university laboratory environment -
were it is expected to yield significant insights into the microstructure
of hydrated, unstained cells.
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ATTRACTIVE ATOMIC FORCE MICROSCOPY FOR DNA SEQUENCING
-
批准号:3505304
-
项目类别:
-
资助金额:$5.0万
-
财政年份:1991
-
负责人:JOSEPH BLANC
-
依托单位:
READ-OUT INSTRUMENTATION FOR X-RAY CONTACT MICROSCOPY
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批准号:3498280
-
项目类别:
-
资助金额:$5.0万
-
财政年份:1990
-
负责人:JOSEPH BLANC
-
依托单位:
海外基金