MULTI-USER COMPUTER SYSTEM FOR AUDITORY RESEARCH

这是一个应用程序1）中央计算机，和2）相关 允许采集、操作和显示解剖结构的设备 与脊椎动物听觉系统生理学研究有关的数据， 伊顿-皮博迪实验室 我们的科学方法是定量追踪信号通过每个 听觉系统的阶段;所研究的信号在听觉系统中是声学的。 外耳、中耳和内耳，感觉中的机械电和化学 细胞，初级神经元中的电，以及 离心系统 该方法要求说明相关的 解剖结构、信号定义和模型制定 for the physiological生理processes过程. 我们对信号的生理学知识 在细胞水平上的行为已经改善，需要将这一点 与此同时，解剖学知识也导致了 计算机辅助解剖（CAA）系统的开发，其应用和 使用正在迅速增加。 Eaton-Peabody实验室（EPL）的研究团队由来自 波士顿地区的四个合作机构 更多的EPL员工 50多人包括声学家，电气工程师， 生物学家、解剖学家、神经化学家、生理学家、心理学家， 耳鼻喉科医生和神经科医生。 实际上所有的工作都是基本的 研究，利用病理材料时，有帮助的。 虽然这 小组率先在生理学中使用计算机，我们的研究现在 严重阻碍了过时和不足的中央计算机。 在 除了需要计算我们的解剖工作，使用 用于各种“例行”任务（图形制作，数据处理， 文本处理）增加了快速增长的额外负载， 以我们现有的设施已经很难处理了。 的添加 VAX-11/750中央处理机及计算机外围设备 我们的解剖学研究将极大地增强我们理解 听觉系统，一个对交流至关重要的系统 在人类中，脊椎动物以许多不同的方式使用， 多样的生态环境。

This is an application for 1) a central computer, and 2) associated equipment to allow acquisition, manipulation, and display of anatomical data related to physiological studies on the vertebrate auditory system in the Eaton-Peabody Laboratory. Our scientific approach is to quantitatively trace signals through each stage of the auditory system; the signals studied are acoustic in the external, middle and inner ears, mechanoelectric and chemical in sensory cells, electrical in primary neurons and electrical and mechanical in centrifugal systems. The approach requires description of relevant anatomical structures, definition of the signals, and formulation of models for the physiological processes. As our physiological knowledge of signal behavior at the cellular level has improved, the need to relate this knowledge to anatomical knowledge at the same time has led to the development of a computer-aided anatomy (CAA) system whose applications and use are increasing rapidly. The Eaton-Peabody Laboratory (EPL) research team consists of personnel from four cooperating institutions in the Boston area. The EPL staff of more than 50 individuals includes acousticians, electrical engineers, biophysicists, anatomists, neurochemists, physiologists, psychologists, otolaryngologists and neurologists. Virtually all of the work is basic research, making use of pathological material when helpful. Although this group pioneered the use of computers in physiology, our research is now seriously hampered by an obsolete and inadequate central computer. In addition to the need to computerize our anatomical work, use of the computer for a variety of "routine" tasks (figure making, data processing, text processing) has added a rapidly growing additional load that is already difficult to handle with our present facilities. The addition of a VAX-11/750 central processor unit and peripheral equipment to computerize our anatomical studies will greatly enhance our efforts to understand the auditory system, a system that is of paramount importance for communication in humans and used in many different ways by vertebrates radiating into diverse ecological niches.