Combined TMS-EEG for early diagnosis of Alzheimer’s disease

阿尔茨海默病的早期诊断是更有效的早期干预的关键。目前的生物标志物价格昂贵，不适合检测疾病初期发生的大脑功能的细微变化。无创脑刺激无痛且价格低廉，可以直接探测有意识的人类的脑功能。该项目将调查这些技术是否可以用来识别阿尔茨海默病早期脑功能障碍的标志。

Early diagnosis of Alzheimer's disease is key to more effective early intervention. Current biomarkers are expensive and are not suited for detecting the subtle changes in brain function that occur during the initial stages of the disease. Non-invasive brain stimulation is pain-free and inexpensive, and can directly probe brain function in conscious humans. This project will investigate whether these techniques might be used to identify markers of early brain dysfunction in Alzheimer’s disease.