Workshop on Roadmapping of Quantitative Understanding of Cleaning & Decontamination

清洁和去污是家庭、医疗保健和工业中无处不在的操作。去除表面上不需要的残留物，以避免产品之间的交叉污染（例如在厨房、食品或制药业），去除污垢层，使表面恢复到其原始状态或性能水平（例如，从窗户、墙壁或热交换器），或者从手术器械（例如在医疗保健中）中消除生物体和生物膜，历史上一直是通过随时间发展的“久经考验”的方法来解决的。这种经验方法不太可能适用于英国和许多其他国家面临的新的清洁和去污挑战，其中包括（a）新的土壤和表面。食品行业需要不断创新，因为它寻求提供营养食品，并遵循不断变化的成分、过敏原和消费者需求指南。在其他地方，NHS和其他医疗保健提供者经常受到包括患者设施卫生状况在内的不同生物体的挑战。(b)危险的土壤。2018年谢尔盖和尤利娅·斯克里帕尔中毒后，斯克里帕尔的房子和其他与诺维乔克物质接触的物品和地点进行了数月的净化工作。英国核工业面临着一系列与反应堆和燃料后处理厂退役有关的新的清洁和去污案例。确定如何在不进行广泛测试的情况下有效地清洁这些表面是至关重要的，因为用于清洁表面的材料本身就被污染了：试验在时间和资源上非常昂贵。(c)资源有限。许多清洁操作使用大量的清洁水，通常是加热的并且通常含有清洁剂。许多食品生产操作的可持续性取决于清洁所花费的时间（降低生产率）以及提供，制备和处理这些水的成本。 本次研讨会将建立在英国和超越清洁和净化操作的定量建模的最先进的状态。它将汇集来自不同学科和行业的专家，最大限度地分享现有知识，并抓住即将到来的挑战。一个关键的交付成果是创建一个路线图，以指导该领域的未来研究。它将采取2.5天的物理会议的形式在2020年9月，然后在2020年11月初的组织者为期1天的网络会议，总结将最终确定。第一天将侧重于建立相关学科的艺术（或科学）状态，邀请演讲者就数学方法、实验技术和数据方法等主题进行一系列主题演讲。这些活动将穿插由活跃的研究人员进行简短的口头介绍，以突出正在进行的工作，并发酵网络。重点将放在目前的工作上。第二天将重点关注挑战，邀请来自行业（包括食品，制药和核能），政府（例如DSTL，DEFRA）和服务（例如水，医院）的演讲。每个演讲之后将讨论所涉及的定量要素，重点是现有科学的差距以及测试、建模和资源中出现的问题。第三天将汇集学习成果，确定研究和路线图未来工作的优先事项。研讨会的结果将在公开存档中提供。

Cleaning and decontamination are ubiquitous operations in the home, healthcare and industry. The removal of unwanted residues from surfaces in order to avoid cross-contamination between products (e.g. in the kitchen, food or pharmaceutical manufacture), the removal of fouling layers to return surfaces to their original condition or level of performance (e.g. from windows, walls or heat exchangers), or the elimination of organisms and biofilms from surgical instruments (e.g. in healthcare) have historically been tackled by 'tried and tested' approaches which have been developed over time. Such empirical approaches are unlikely to be suitable for the new cleaning and decontamination challenges which the UK and many other nations face, which include(a) New soils and surfaces. The food industry is subject to continuous innovation as it seeks to supply nutritious food subject to evolving guidance on ingredients, allergens and consumer requirements. Elsewhere, the NHS and other healthcare providers are regularly challenged by different organisms comprising the hygienic status of patient facilities. (b) Dangerous soils. The poisoning of Sergei and Yulia Skripal in 2018 was followed by many months of work to decontaminate the Skripal's house and other items and locations which had come into contact with the Novichok substance. The UK nuclear industry faces a range of new cleaning and decontamination cases associated with the decommissioning of reactors and fuel reprocessing plants. Determining how to clean these effectively without extensive testing is critical as the materials used to clean the surfaces are themselves contaminated: trials are very costly in time and resources. (c) Limited resources. Many cleaning operations employ large volumes of clean water, often heated and often containing cleaning agents. The sustainability of many food manufacturing operations is determined by the time spent cleaning (reducing productivity) and the cost of providing, preparing and treating this water. This workshop will establish the state of the art in quantitative modelling of cleaning and decontamination operations in the UK and beyond. It will bring together experts from different disciplines and industries to maximise the sharing of existing knowledge and capture the challenges on the horizon. A key deliverable is the creation of a roadmap to guide future research in this area.It will take the form of a 2.5 day physical meeting in September 2020 followed by a 1 day web-conference of the organisers in early November 2020 where the summaries will be finalised. Day 1 will focus on establishing the state of the art (or science) in related disciplines, with a series of keynote presentations by invited speakers on topics ranging from mathematical methods to experimental techniques and data methods. These will be interspersed by sessions with short oral presentations by active researchers in order to highlight ongoing work, and ferment networking. The emphasis will be on current work. Day 2 will focus on challenges, with invited presentations from industry (including food, pharma and nuclear), government (e.g. DSTL, DEFRA) and services (e.g. water, hospitals). Each presentation will be followed by a discussion of the quantitative elements involved, focusing on gaps in existing science and issues arising in testing, modelling and resources.Day 3 will bring learnings together to identify priorities in research and future work for the roadmap.The findings from the Workshop will be made available on a publicly available archive.