GENETICS AND PHYSIOLOGY OF VECTOR CAPACITY IN ANOPHELINE MOSQUITOS

按蚊的生物学正在研究中， 这些病媒传播疟疾的能力。 基因的，分子的， 生物化学和免疫学研究正在试图描述 在蚊子体内增强或延缓疟疾的发展 寄生虫，重点是动合子，卵囊， 子孢子 为了促进这些研究：1）克隆的方法正在改进 并将基因转移到蚊子的生殖系中，2）系统正在被 评估蚊子胚胎的冷冻保存，以增加我们的 储存遗传物质的能力。 识别、克隆和转置调控基因的能力 使蚊子对寄生虫发育不敏感的机制 应促进基于以下方面制定控制战略： 引入不能 传播疟疾

The biology of anopheline mosquitoes is being studied in relation to the capacity of these vectors to transmit malaria. Genetic, molecular, biochemical, and immunological studies are seeking to describe mechanisms in the mosquito that enhance or retard development of the malaria parasite with emphasis on the behavior of ookinetes, oocysts, and sporozoites. To facilitate these studies: 1) methods are being improved for cloning and transposing genes into mosquito germ lines, and 2) systems are being evaluated for the cryopreservation of mosquito embryos to increase our capacity to store genetic material. The ability to identify, clone, and transpose genes that regulate mechanisms that render mosquitoes refractory to parasite development should facilitate development of control strategies based on the introduction into the field of mosquito populations incapable of transmitting malaria.