Danger Ideation Reduction Therapy For Obsessive-Compulsive Checkers: A Randomised Controlled Trial

强迫症（OCD）是一种精神疾病，影响高达3%的普通人群。患有这种疾病的人会经历令人不快的侵入性想法，他们感到痛苦，并有强烈的冲动去执行特定的行为。对火灾和入室盗窃的恐惧是常见的，对电器和锁的过度检查可能需要一天好几个小时。强迫症患者是最大的强迫症亚群之一。由于这种情况非常耗时，社交和职业功能往往受到严重限制。许多患者也会经历极端的社会孤立和抑郁。世界卫生组织将这种疾病列为所有疾病负担原因中的第20位。有效的干预措施的发展可以大大减少这种致残性焦虑症的经济和社会负担。本项目的目的是：（1）比较一种新的治疗方法（减少危险思维疗法）与暴露和反应预防（ERP）的治疗效果;假设：（1）接受12次DIRT的受试者将显示出比接受ERP的受试者更大的治疗后和随访的神经病学减少。

Obsessive-compulsive disorder (OCD) is a psychiatric disorder that affects up to 3% of the general population. People with the disorder experience unpleasant intrusive thoughts that they find distressing and have a strong urge to perform particular behaviours. Fears about fire and burglary are common and excessive checking of electrical appliances and locks can take many hours a day. Checkers represent one of the largest OCD sub-groups. Because of the time-consuming nature of the condition, social and occupational functioning is often severely restricted. Many sufferers will also experience extreme social isolation and depression. The World Health Organisation ranks this disorder as 20th among all causes of burden of disease. The development of effective interventions could substantially reduce the economic and social burden of this disabling anxiety disorder. The aim of this project is: (1) to compare the therapeutic efficacy of a new treatment approach (Danger Ideation Reduction Therapy) with that of Exposure and Response Prevention (ERP); It is hypothesised that: (1) subjects who receive 12 sessions of DIRT will show greater post-treatment and follow-up reductions in symptomatology than subjects who receive ERP.