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METHODS FOR THE CALCULATION OF MINIMAL ELECTROPHORESIS TIME FOR DNA SEQUENCING

METHODS FOR THE CALCULATION OF MINIMAL ELECTROPHORESIS TIME FOR DNA SEQUENCING
DNA测序最短电泳时间的计算方法
批准号:
3874223
负责人:
A ALDROUBI
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至

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中文摘要
翻译
本研究的目的是找到一种数学方法, 一种是缩短DNA测序所需的电泳时间。 的 要开发的算法是根据迁移率计算 和频带扩展程度(色散系数)的估计, 两个迁移最慢的组分, 通过电泳对任何分子混合物的完全分离。 因此,最小迁移路径长度和对应位置 在给定的场, 强度、离子强度和温度。
英文摘要
The purpose of this study is to find a mathematical approach that allows one to shorten the electrophoresis time required for DNA sequencing. The algorithms to be developed are to calculate, on the basis of the mobilities and an estimate of the degree of band spreading (dispersion coefficient) of the two most slowly migrating components, the time required for the complete resolution of any mixture of molecules by electrophoresis. Accordingly, the minimal migration path length and corresponding position of the detector in a gel can be mathematically defined at a given field strength, ionic strength, and temperature.
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PROCESSING OF HIGH RESOLUTION ELECTRON MICROGRAPHS
WAVELET TRANSFORM APPLICATIONS TO BIOLOGY
FUNCTIONAL ANALYSIS AND APPLICATIONS TO BIOMEDICAL IMAGE PROCESSING
MATHEMATICAL METHODS IN GEL ELECTROPHORESIS
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