Defining the role of Nedd4 in neural crest cell development

神经脊细胞是一种特殊的干细胞，在胚胎发育过程中会产生许多组织和器官。我们最近发现了一种调节蛋白在神经脊细胞中的重要作用。我们的研究旨在了解这种蛋白质如何影响心脏和面部骨骼等结构的生长。了解这些过程是对高度流行的先天性出生缺陷实施诊断和预防医学的最终目标。

Neural crest cells are specialised stem cells that give rise to many tissues and organs during embryonic development. We recently identified an essential role for a regulatory protein in neural crest cells. Our research is aimed at understanding how this protein influences the growth of structures such as the heart and facial skeleton. Understanding these processes underpins the ultimate goal of implementing diagnostic and preventative medicine for highly prevalent congenital birth defects.