Identifying the embryonic origin of neuroblastoma

识别神经母细胞瘤的胚胎起源

• 批准号: nhmrc : 1008426
• 负责人: Dr Quenten Schwarz
• 金额: $ 36.61万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/identifying-embryonic-origin-neuroblastoma/109311
• 关键词: Identifying; embryonic; origin; neuroblastoma

In this grant we will take advantage of procedures uniquely available to the applicant to identify the cell type from which the most prevalent extra cranial solid tumour in children, neuroblastoma (NB), arises during embryonic development. Further studies on this specific cell type will identify the factors controlling their correct embryonic development. Assessment of these molecules as therapeutic targets will then identify novel treatments to inhibit disease progression.

在这笔资助中，我们将利用申请人独有的程序来鉴定儿童中最常见的颅外实体瘤神经母细胞瘤（NB）在胚胎发育过程中产生的细胞类型。对这种特定细胞类型的进一步研究将确定控制其正确胚胎发育的因素。对这些分子作为治疗靶点的评估将确定抑制疾病进展的新疗法。